Protein Alignment Polr3B and Polr3b

DIOPT Version :10

• Sequence 1: NP_523706.1
• Gene: Polr3B / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_001178807.1
• Gene: Polr3b / 362858
• RGDID: 1565311
• Length: 1133
• Species: Rattus norvegicus
• Alignment Length: 1120
• Identity: 772/1120 - (68%)
• Similarity: 932/1120 - (83%)
• Gaps: 6/1120 - (0%)

  Fly    22 KDWSVPIKPLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYL 86
            ::.:.||..:.|||:|:||||:|||||||||||||:||||:||||:||||.|||.|||::|||||
  Rat    14 EELAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYL 78

  Fly    87 DVRVGKPDIDDGFNITKATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCS 151
            ::.||.||:::.||:|:..:||||||||.|||||||||||||||:|||.||.|.|||||:|||.|
  Rat    79 NIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSS 143

  Fly   152 NCALTGKSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNKMLTE-DFNGVVQCQVTSSTH 215
            ||.||||:..|.:|||||||||||||:|:|.|||||||||||.|:::.| |..|.|...||||||
  Rat   144 NCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGAVGASVTSSTH 208

  Fly   216 EKKSRTLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLIGIDSKSQNRFGASLIDAY 280
            ||||||.:..|.|::||:||::::|||||:||||:||.|||||..:||.:......||.||.:..
  Rat   209 EKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQ 273

  Fly   281 NLKVFTQQRALEYMGSKLVVKR-FQSATTKTPSEEARELLLTTILAHVPVDNFNLQMKAIYVSMM 344
            ..::|||.:||:|:|:|:..:| :.....||..|||||||.:|||.||||..||.:.|.||.::|
  Rat   274 KAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVM 338

  Fly   345 VRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPKVKAAQFDV 409
            ||||:.|:.|..: |||||||||||||||.|||::||||||:.|.|:|.|||:.|||.:||||||
  Rat   339 VRRVILAQGDNKV-DDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDV 402

  Fly   410 VKHMRAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSG 474
            |||||..|||.|:.:|||:|||::|||||:|.||||||||||||||||||||::|||||||||||
  Rat   403 VKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSG 467

  Fly   475 PRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNPIN 539
            |||||||||||||||||||||||||||||||||||||::|:.|::.:|.|.||||:..:.|..::
  Rat   468 PRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAGNLGVEDVNLLCGEELS 532

  Fly   540 NPNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRPYV 604
            .|||||||:|||:||:..:||.||...|.|||.|.:..:||:.|:.|.||:||.:|||||||||:
  Rat   533 YPNVFLVFLNGNILGVIRDHKKLVSTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYI 597

  Fly   605 IVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIEPF 669
            ||:.::|.|...|::||.:|.|.|:|||.:.|:||||||||||..||..|..|...|||||||||
  Rat   598 IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPF 662

  Fly   670 TLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIEL 734
            |||||||||:|||||||||||||||||||||||.|||||:||||:|||.|.||..||||:|||||
  Rat   663 TLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIEL 727

  Fly   735 TNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMG 799
            .:|:||||||||||||||||||||||||:|||||:|||:||||||||:|||:|||.|||||::||
  Rat   728 IDFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMG 792

  Fly   800 PMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPLQGQSA--QVPYTAVPI 862
            ||.||.|.|.|::|::||.|||.:|||:|:|||:::||.||.||.: ||:|.:.  |..|..|||
  Rat   793 PMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI-PLEGSNVPQQPQYKDVPI 856

  Fly   863 SYKGPEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDF 927
            :|||...||||:||:|:|||:.||||:||||||.||||||||||||||||.||||.||||||.|.
  Rat   857 TYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDS 921

  Fly   928 GICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELERHGFNYVGK 992
            |||||:|||||||||||||||.:|||.||||:|:|:||||||||||||:|:..:|.|||:||:||
  Rat   922 GICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGK 986

  Fly   993 DFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEME 1057
            |:..|||||.|||||||.||||||||||||.||||||||||:||||||||:||||:|||||||||
  Rat   987 DYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEME 1051

  Fly  1058 RDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMPYACKLLFQE 1122
            |||||.||||||::|||||||||||||||..||.:.|..|||:|:||.:||.:.:||||||||||
  Rat  1052 RDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQE 1116

  Fly  1123 LTSMNVVPKMILENY 1137
            |.|||::|::.|..|
  Rat  1117 LQSMNIIPRLKLAKY 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr3B	NP_523706.1	RNA_pol_B_RPB2	47..1133	CDD:238353	757/1089 (70%)
		RNA_pol_Rpb2_4	546..607	CDD:428012	34/60 (57%)
		RNA_pol_Rpb2_5	628..668	CDD:428013	25/39 (64%)
Polr3b	NP_001178807.1	RNA_pol_B_RPB2	39..1127	CDD:238353	757/1089 (70%)
		RNA_pol_Rpb2_4	539..600	CDD:428012	34/60 (57%)
		RNA_pol_Rpb2_5	621..661	CDD:428013	25/39 (64%)