Protein Alignment Polr3B and rpc-2

DIOPT Version :10

• Sequence 1: NP_523706.1
• Gene: Polr3B / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_498192.2
• Gene: rpc-2 / 175767
• WormBaseID: WBGene00017300
• Length: 1154
• Species: Caenorhabditis elegans
• Alignment Length: 1129
• Identity: 687/1129 - (60%)
• Similarity: 860/1129 - (76%)
• Gaps: 21/1129 - (1%)

  Fly    30 PLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYLDVRVGKPD 94
            ||.:||.||||||:|:||||||:.||:||:..:|:.|:.:|:.:||.|:|.|||||||:|:|||.
 Worm    24 PLEDKWLLVPAFLKVRGLVKQHLVSFDHFVQEEIRSIMLSNQKITSDANPNFYLKYLDIRIGKPS 88

  Fly    95 IDDGFNIT-KATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCSNCALTGK 158
            .::|.|:| ...||.||||||.||||||:||||||||.||:.:.:|:|||||:|||.|.|.|...
 Worm    89 SEEGLNMTHDKITPQECRLRDMTYSAPISVDIEYTRGNQRVFKKDLIIGRMPIMLRSSKCILRDL 153

  Fly   159 SEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNK-MLTEDFNGVVQCQVTSSTHEKKSRTL 222
            :|.||:::.|||.||||||||:|.|||||||||||.|: |:..:.:..:||:|.|||.|:||:|.
 Worm   154 AEEELARVQECPYDPGGYFVVKGSEKVILIQEQLSKNRIMVGRNSSKELQCEVLSSTSERKSKTY 218

  Fly   223 VLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLIGIDSKSQNRFGASLIDAYNLKVFTQ 287
            |..|.|||.::||.:|||:|:.:||||:||.||.:|.|.||.:.|..:.|..:|.::.|..|:||
 Worm   219 VTMKKGKYSVRHNQLTDDVPVSIIFKAMGVESDFDIVSTIGHEEKYVSAFAQTLEESINAGVYTQ 283

  Fly   288 QRALEYMGSKLVVKRF--------QSATTKTP--SEEARELLLTTILAHVPVDNFNLQMKAIYVS 342
            |:||.|:.||:..::|        .|.:..||  ..||.:.|..:::.|:...:.|.:|||||:.
 Worm   284 QQALAYVTSKVKARKFTPFGSLPGTSVSVLTPPKEHEAVDFLSNSMITHIACPDGNFKMKAIYLG 348

  Fly   343 MMVRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPKVKAAQF 407
            :|.||::..||.:...||||:||||||||||||||::|||:|||.|.|||.|||..:.|..||..
 Worm   349 LMTRRLIQTELGENGLDDRDFYGNKRLELAGSLLSLLFEDVFKRFNSELKRIADNALMKTMAAPL 413

  Fly   408 DVVKHMRAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKV 472
            |:|||||...||..:.:|:|:|||.||||:|||.||||||||||||||||||||:||.|||||||
 Worm   414 DIVKHMRQDMITNTIVNAMSTGNWIIKRFRMERLGVTQVLSRLSYISALGMMTRINSTFEKTRKV 478

  Fly   473 SGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNP 537
            |||||||||||||||||||||||||||||||||::||||:.:|:||:.:..|:||||:..|..:.
 Worm   479 SGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALISHITTDSDEKPVLRLLLNSGVEDLHNVHFSH 543

  Fly   538 INNPNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRP 602
            :|.|...|:|:||.::|..::.:.:|:.:|.:||.|.:..:|||..|.|.|.::|.:||||||||
 Worm   544 VNKPENTLIFLNGVLIGTAVDPERVVKAVRDLRRSGLLSEFVSVSRSLTNRSVFISSDGGRLCRP 608

  Fly   603 YVIVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIE 667
            |:||:|..|::.|.|:.||..|...|:||:.||::|||||||.||:.||....:|...|||||||
 Worm   609 YIIVKNGTPMLTQAHVQELKEGKMIFEDFVDDGIVEYLDVNEMNDALIAVYGREIGPETTHLEIE 673

  Fly   668 PFTLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTI 732
            |||||||||||:|||||||||||||||||||||||.|.|||:.||||:||.|.||..|:||||||
 Worm   674 PFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIAYNQQKRIDSIMYLLCYPQRPLVKSKTI 738

  Fly   733 ELTNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRI 797
            |||||:|||||.|..:||||||||||||||:|||||:|||||||||||:.|.|.|:|.||||||:
 Worm   739 ELTNFEKLPAGANGIIAVMSYSGYDIEDALVLNKASLDRGYGRCLVYKHVKGTAKKYPNQTFDRL 803

  Fly   798 MGPMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVT---------SMNPLQGQSA 853
            :||..|..|.|.||||..||.:|||..|.::..||.:|||.||.|:         |.|.:.....
 Worm   804 LGPALDPNTRKPIFKHKNLDQEGIVFAGARIMPKQTIINKHMPVVSGESGPGASASANTIGIAGR 868

  Fly   854 QVPYTAVPISYKGPEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVE 918
            ||.|..|.|:||.|.|||.|||:::.|.:|..|.|:||||||.||:|||||||||||||.|||.:
 Worm   869 QVDYKDVSITYKTPTPSYAERVLLTYNEDEAHLFKVLLRQTRRPELGDKFSSRHGQKGVCGLIAQ 933

  Fly   919 QEDMPFNDFGICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELE 983
            ||||||||.|:.|||||||||:||||||||.:|||.||||::.|.:||||||||.:|:|:..||.
 Worm   934 QEDMPFNDLGMVPDMIMNPHGYPSRMTVGKLMELLSGKAGVVNGTYHYGTAFGGDQVKDVCEELA 998

  Fly   984 RHGFNYVGKDFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSRE 1048
            ..|:||:|||...|||||.||.||||.||:|||||||||.||||||||||:|.||||||:|||||
 Worm   999 ACGYNYMGKDMLTSGITGQPLSAYIYFGPIYYQKLKHMVLDKMHARARGPRAALTRQPTEGRSRE 1063

  Fly  1049 GGLRLGEMERDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMP 1113
            ||||||||||||||:||||||::||||:|||.|:||||..||.:....||..|:||.:::.|.:|
 Worm  1064 GGLRLGEMERDCLIAYGASMLLIERLMVSSDEFKVDVCTGCGVIGSKGWCQKCRSSKSMANIKIP 1128

  Fly  1114 YACKLLFQELTSMNVVPKMILENY 1137
            ||||||||||.|||:||::.|..|
 Worm  1129 YACKLLFQELQSMNIVPRLDLARY 1152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr3B	NP_523706.1	RNA_pol_B_RPB2	47..1133	CDD:238353	673/1106 (61%)
		RNA_pol_Rpb2_4	546..607	CDD:428012	26/60 (43%)
		RNA_pol_Rpb2_5	628..668	CDD:428013	23/39 (59%)
rpc-2	NP_498192.2	RNA_pol_B_RPB2	41..1148	CDD:238353	673/1106 (61%)
		RNA_pol_Rpb2_4	552..613	CDD:428012	26/60 (43%)
		RNA_pol_Rpb2_5	634..674	CDD:428013	23/39 (59%)