Protein Alignment Polr3B and polr3b

DIOPT Version :10

• Sequence 1: NP_523706.1
• Gene: Polr3B / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_001121521.1
• Gene: polr3b / 100158643
• XenbaseID: XB-GENE-5799940
• Length: 1134
• Species: Xenopus tropicalis
• Alignment Length: 1116
• Identity: 765/1116 - (68%)
• Similarity: 925/1116 - (82%)
• Gaps: 7/1116 - (0%)

  Fly    27 PIKPLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYLDVRVG 91
            |:..:.|||||:||||:|||||||||||||:|||.:||||:||||.|||.|||::|||||::.||
 Frog    19 PVDTVQEKWKLLPAFLKVKGLVKQHIDSFNYFINDEIKKIMKANEKVTSDADPMWYLKYLNIYVG 83

  Fly    92 KPDIDDGFNITKATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCSNCALT 156
            .||:::.||:|:..:||||||||.|||||||||||||||:|||.||.|.|||||:|||.|||.||
 Frog    84 LPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLT 148

  Fly   157 GKSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNKMLTE-DFNGVVQCQVTSSTHEKKSR 220
            ||:..|.:|||||||||||||:|:|.|||||||||||.|:::.| |..|.|...|||||||||||
 Frog   149 GKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGTVGASVTSSTHEKKSR 213

  Fly   221 TLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLIGIDSKSQNRFGASLIDAYNLKVF 285
            |.::.|.|::|||||::|:||||.:||||:||.|||||..:||.:......|..||.:....::|
 Frog   214 TNLVVKQGRFYLKHNTLTEDIPIAIIFKAMGVESDQEIVQMIGTEEHVIAAFAPSLEECQKAQIF 278

  Fly   286 TQQRALEYMGSKLVVKRF--QSATTKTPSEEARELLLTTILAHVPVDNFNLQMKAIYVSMMVRRV 348
            ||.:||:::|:|:..:|.  .|...|:..:||||||.:|||.||||..|:.:.|.||:::|||||
 Frog   279 TQMQALKFIGNKVRRQRMWGSSGPKKSKIDEARELLASTILTHVPVKEFHFRTKCIYIAVMVRRV 343

  Fly   349 MAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPKVKAAQFDVVKHM 413
            :.|: .....|||||||||||||||.|||::||||||:.|.|:|.|||:.|||.:||||||||||
 Frog   344 ILAQ-GANKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHM 407

  Fly   414 RAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSL 478
            |..|||.|:.:|||||||::|||||:|.||||||||||||:|||||||::|||||||||||||||
 Frog   408 RQDQITNGMVNAISSGNWSLKRFKMDRQGVTQVLSRLSYIAALGMMTRISSQFEKTRKVSGPRSL 472

  Fly   479 QPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNPINNPNV 543
            |||||||||||||||||||||||||||||||||::|:.|::.:|.|.||||:..:.|..::..||
 Frog   473 QPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIIKLAANLGVEDVNLLCGEELSYANV 537

  Fly   544 FLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRPYVIVEN 608
            ||||:|||:||:..:|:.||...|.|||.|.:..:||:.|:.:.||:||.:|||||||||:||:|
 Frog   538 FLVFLNGNILGVIRDHQKLVNTFRLMRRAGYINEFVSISTNISDRCVYISSDGGRLCRPYIIVKN 602

  Fly   609 RRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIEPFTLLG 673
            :|..|...|:.||::|.|.|:|||.:.|:||||||||||..:|..|..|...|||||||||||||
 Frog   603 QRSAVTNKHIQELSQGYRSFEDFLHESLVEYLDVNEENDCNVALYEHTITKHTTHLEIEPFTLLG 667

  Fly   674 VCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELTNFD 738
            |||||:|||||||||||||||||||||||.|||||:||||:|||.|.||..||||:|||||..|:
 Frog   668 VCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQRPMVKTKTIELIEFE 732

  Fly   739 KLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGPMKD 803
            ||||||||||||||||||||||||:|||||:|||:||||||||:|||:|||:|||||::||||.|
 Frog   733 KLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYSNQTFDKVMGPMLD 797

  Fly   804 ALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPLQGQSA--QVPYTAVPISYKG 866
            |.|.|.|::|::||.|||.:|||:|:|||:::||.||.|| ..||:|.|.  |..|..|||:|||
 Frog   798 ANTRKQIWRHEILDADGICSPGEKVENKQVLVNKYMPTVT-QTPLEGSSVPQQPQYKDVPITYKG 861

  Fly   867 PEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDFGICP 931
            |..||||:||:|:|||:.|||||||||||.||||||||||||||||.||||.||||||.:.||||
 Frog   862 PTDSYIEKVMISSNAEDAFLIKILLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCETGICP 926

  Fly   932 DMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELERHGFNYVGKDFFY 996
            |:||||||:||||||||.:|||.||||:|:|:||||||||||||:|:..:|.|:|:||:|||:..
 Frog   927 DIIMNPHGYPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLIRYGYNYLGKDYVT 991

  Fly   997 SGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEMERDCL 1061
            |||||.|||||||.||||||||||||.||||||||||:||||||||:||||:|||||||||||||
 Frog   992 SGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCL 1056

  Fly  1062 ISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMPYACKLLFQELTSM 1126
            |.||||||::|||||||||||||||..||.:.|..|||||:||.:||.:.:|||||||||||.||
 Frog  1057 IGYGASMLLLERLMISSDAFEVDVCGKCGLLGYSGWCHFCKSSCHVSSLRIPYACKLLFQELQSM 1121

  Fly  1127 NVVPKMILENY 1137
            |::|::.|..|
 Frog  1122 NIIPRLKLAKY 1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr3B	NP_523706.1	RNA_pol_B_RPB2	47..1133	CDD:238353	750/1090 (69%)
		RNA_pol_Rpb2_4	546..607	CDD:428012	32/60 (53%)
		RNA_pol_Rpb2_5	628..668	CDD:428013	24/39 (62%)
polr3b	NP_001121521.1	RNA_pol_B_RPB2	39..1128	CDD:238353	750/1090 (69%)
		RNA_pol_Rpb2_4	540..601	CDD:428012	32/60 (53%)
		RNA_pol_Rpb2_5	622..662	CDD:428013	24/39 (62%)