Protein Alignment: Mppe and MPPE1

• Sequence 1: NP_001286327.1
• Gene: Mppe
• FlyBaseID: FBgn0259985
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_006722403.1
• Gene: MPPE1
• HGNCID: 15988
• Length: 397
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 91/423 (22%)
• Similarity: 156/423 (37%)
• Gaps: 136/423 (32%)

  Fly    18 VALTLLLVFFNEFIVYYMA--QSSWQPIDCKL---DNCTR-----LLLIADPQILGNSYDRSSHS 72
            :|:...::.|.||::||:|  |.:|..:....   :..||     .:.:||..:||......
Human    27 IAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHW--- 88

  Fly    73 PLARYDSDRYLAKTFERALAFTQPHIIVFLGDLLDEGNIATAQEYKQYVQRFRRIYQNKNYKKFR 137
             |.:...:..:.:.|:.||...||.::..|||:.|||..:|.:.:...|:||::::::.::.:.:
Human    89 -LDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLK 152

  Fly   138 MISAFFQRVHVPGDNDIGGENGDYISNSNQ-RRFENEFMSEDLFDYDNRLRFFKINRMLLDFSNP 201
            :::         |::|||..   |..|:.: .|||..|.||.||.:.. :.|..:|.:.|:....
Human   153 VVA---------GNHDIGFH---YEMNTYKVERFEKVFSSERLFSWKG-INFVMVNSVALNGDGC 204

  Fly   202 DRDNNADRLRIGVSH------------------------APLLIGGGPLLRAIISD--------- 233
            ...:..:...|.|||                        ||:|:...||.|.  ||
Human   205 GICSETEAELIEVSHRLNCSREQARGSSRCGPGPLLPTSAPVLLQHYPLYRR--SDANCSGEDAA 267

  Fly   234 ---------------------------LDPHIIFSGHWHESRIFIYPSTKVINFYENSVRHFDLK 271
                                       |.|.::.|||.|.:
Human   268 PAEERDIPFKENYDVLSREASQKLLWWLQPRLVLSGHTHSA------------------------ 308

  Fly   272 ALKEQEHS--YLEIMVPTCSYR-MGKSKIGLGYAVLENYNLSYTVLWQPNRFILLFTYVFWGLFV 333
              .|..|.  ..|:.||:.|:| .......:|.....:|.||...|  |...::|..|.     .
Human   309 --CEVHHGGRVPELSVPSFSWRNRNNPSFIMGSITPTDYTLSKCYL--PREDVVLIIYC-----G 364

  Fly   334 VCGFVVFKMMTR-----CPF-----RVAKRQT 355
            |.||:|...:|.     .||     .:.||:|
Human   365 VVGFLVVLTLTHFGLLASPFLSGLNLLGKRKT 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mppe	NP_001286327.1	Metallophos	52..246	CDD:278574	56/260 (22%)
		MPP_Cdc1_like_1	54..293	CDD:277373	62/303 (20%)
MPPE1	XP_006722403.1	Metallophos	70..306	CDD:278574	54/255 (21%)
		MPP_MPPE1	73..330	CDD:277372	62/302 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3662
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950		0	Normalized mean entropy	S3042
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1094620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1923
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.890