DRSC/TRiP Functional Genomics Resources

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Protein Alignment: exp and SMAD2

Sequence 1:NP_725091.1 Gene:exp FlyBaseID:FBgn0033668 Length:1025 Species:Drosophila melanogaster
Sequence 2:NP_001003652.1 Gene:SMAD2 HGNCID:6768 Length:467 Species:Homo sapiens

Alignment Length:185 Identity:42/186 (23%)
Similarity:80/186 (43%) Gaps:26/186 (14%)


  Fly    50 TQIDDEIWAKVIVFERNRRVAKAY-ARAPVLTINGSDDGFDGMRIGLCGFDNPMRDQKTDEMKRV 113
            |..:...|..:..:|.|:||.:.: |..|.||::|..|..:..|..|....|..|:...:..:|.
Human   267 TYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRH 331

  Fly   114 IGQGVKIKMDDAGNILIRRYAKSNVYVKSTASSPNEETSIG---AEILKLP---NQALESEKIVK 172
            ||:||::.. ..|.:.....:.|.::|:    |||.....|   |.:.|:|   |        :|
Human   332 IGRGVRLYY-IGGEVFAECLSDSAIFVQ----SPNCNQRYGWHPATVCKIPPGCN--------LK 383

  Fly   173 LFDMKKFQSNVNRELRRAYPDRRRLETQCLSAVAFVKS------ENDILECPIWV 221
            :|:.::|.:.:.:.:.:.:....:|...|...::|||.      ...:...|.|:
Human   384 IFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 438

Known Domains:


GeneSequenceDomainRegion External IDIdentity
expNP_725091.1 MH2 56..224 CDD:294046 41/180 (23%)
SMAD2NP_001003652.1 MH1_SMAD_2_3 8..172 CDD:199815
PY-motif 221..225
MH2_SMAD_2_3 266..456 CDD:199826 42/186 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 0 Normalized mean entropy S3018
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.950

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