Protein Alignment cuff and DXO1

DIOPT Version :10

• Sequence 1: NP_610709.1
• Gene: cuff / 36269
• FlyBaseID: FBgn0260932
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_010658.3
• Gene: DXO1 / 851976
• SGDID: S000002778
• Length: 442
• Species: Saccharomyces cerevisiae
• Alignment Length: 327
• Identity: 62/327 - (18%)
• Similarity: 115/327 - (35%)
• Gaps: 90/327 - (27%)

  Fly    28 KPVSNGWFAWSPIGQFEPNSQKVPYVVVPPSIKFPIS--LRYKDSPPKLEKKPNIFLDNMLQYIE 90
            |..|:...:..|..|.:...::.|.::..|...|..:  ..:...||:     :||.::....:.
Yeast    38 KTTSDSSSSRKPSQQRDNYRKRRPKLICIPYTSFLHTGMHNFLTKPPR-----DIFHESKEVALF 97

  Fly    91 SSSYMYVMVRNNQQAQLNANIVCTSEVLELMMCAPYEKKTGWSLGVTRYRN-----TMYICRIDV 150
            ::...|.::|.:....|..:|   :|:.|..:....::|..: ||...:.|     .|.|..:|.
Yeast    98 TNGRAYTILRKDLIPNLKESI---AELYESSLLEAKKRKVPY-LGHDLFANIDEFVPMTISELDS 158

  Fly   151 EQP--DPIDQ---DN--------------------LKRAMQEFWLRNLRTHCV---FENGIKMHQ 187
            ..|  ..|:.   ||                    :...|..|..||.:|..:   ...|:....
Yeast   159 VSPCFSYIENWILDNPGKDFKIGKKFTVVTTRHHIVDLTMHLFNRRNRQTSLIVTYMGAGLLSFC 223

  Fly   188 HNQSSEEHLRFHGVFSFDLNGNRVLF----------DSPVLAEM-----PSTTLNGSALS-WVDL 236
            .|...:..:...|::|.|.|..::.:          ::..:|::     |..:|..|.|| .:.|
Yeast   224 RNVKKDSQMSKEGIYSNDPNMKKICYSGFEFENWVTENSKVADLTGSKCPIFSLVESKLSEEIGL 288

  Fly   237 QIR--------------------PMFMSRLDWPEHN---RTEALKWWVKCFLLGIESLYIARRDE 278
            .||                    |:.|       ||   |.:.||.||:..||....:.|..||.
Yeast   289 LIRCEMDAFNPVSETNTELKCFAPLSM-------HNSNHRRKLLKTWVQTGLLPNSDIMIGLRDS 346

  Fly   279 NA 280
            ::
Yeast   347 HS 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cuff	NP_610709.1	DUF6454	<32..>69	CDD:437887	5/38 (13%)
		RAI1	<257..284	CDD:462550	9/24 (38%)
DXO1	NP_010658.3	None