DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13192 and mec-15

DIOPT Version :9

Sequence 1:	NP_610702.1	Gene:	CG13192 / 36259	FlyBaseID:	FBgn0033653	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_496207.1	Gene:	mec-15 / 174587	WormBaseID:	WBGene00003177	Length:	406	Species:	Caenorhabditis elegans

Alignment Length:	148	Identity:	30/148 - (20%)
Similarity:	55/148 - (37%)	Gaps:	51/148 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LCFQESDR--LLAGTIKGSVFLWDLQTNRSALHFEVGSDPITSLHHTPDRLVTQEKGGTITMFSI 85
            :.|:.:::  .|:|:...::.||.::..|:      |.|             |::...|:
Worm   110 MLFENNNKQFCLSGSRDRTIRLWSIENARN------GED-------------TEQNPWTV----- 150

  Fly    86 GGSSYVKERSIPGNHLGFCRSALHTNTSKTNEQLLFYPCE-ESSIGVLHVTDAAAPTQILVPDDP 149
                 .|:.:.   |.|:..:....:|| ||    ||... :|::...|:||..|
Worm   151 -----AKDDTA---HSGWIWNMAQESTS-TN----FYTTSWDSTVKSWHITDNGA---------- 192

  Fly   150 QLPKLGSVTCFKPFECAS 167
             |..|.||......:|.|
Worm   193 -LQNLNSVNVGSAAQCIS 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13192	NP_610702.1	WD40	<5..321	CDD:225201	30/148 (20%)
		WD40 repeat	62..98	CDD:293791	3/35 (9%)
		WD40 repeat	103..147	CDD:293791	11/44 (25%)
		WD40 repeat	200..245	CDD:293791
		WD40	201..>321	CDD:295369
		WD40 repeat	247..282	CDD:293791
mec-15	NP_496207.1	F-box-like	9..52	CDD:315592
		WD40	88..322	CDD:330360	30/148 (20%)
		WD40 repeat	106..154	CDD:293791	11/72 (15%)
		WD40 repeat	162..197	CDD:293791	12/50 (24%)
		WD40 repeat	204..241	CDD:293791	2/6 (33%)
		WD40 repeat	247..286	CDD:293791
		WD40 repeat	290..310	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157489
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930