Protein Alignment Tret1-2 and HXT8

DIOPT Version :10

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_012321.1
• Gene: HXT8 / 853216
• SGDID: S000003750
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 129/515 - (25%)
• Similarity: 222/515 - (43%)
• Gaps: 58/515 - (11%)

  Fly    14 SVPADGLKANFTFSQ-----------------VLAALSV-SLCSLVVGFVSAY---TSPALVSMT 57
            |||.  ::.|..||:                 ..|.:|: .||....||:|.:   |....|:.|
Yeast    32 SVPT--VEENKDFSEYNGEEAEEVVVPEKPASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQT 94

  Fly    58 D--RTITSFEVTKDA-------GSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSS 113
            |  |...::..:|:.       ...:..|..:.:..|.:....|.:..||...::...|.::|..
Yeast    95 DFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGI 159

  Fly   114 LL-IACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTL----GLLPTALGNIGILV 173
            :: ||..........||.:.|...|..|:..|:.:.||....:||||    .|:.|....:|...
Yeast   160 VIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCT 224

  Fly   174 CYVAGSFMN---WSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEAD-- 233
            .|...::.|   |.:...|..|..:..:..|..:||:||:.|..|:.|:|:.:.........|
Yeast   225 NYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDP 289

  Fly   234 -VEPELKELMQSQADADRQATQNTCLELFKRNN--LKPLSISLGLMFFQQFSGINAVIFYTVQIF 295
             |..|: :|:.:..:|:......:..|||.|..  .:.|::::.:...||.:|.|...:|...||
Yeast   290 AVVAEI-DLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIF 353

  Fly   296 KDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKAH-- 358
            |..|.. ||..::|::|:|||.:.|..:..:|:|||:..|.:....|...:.|.......:.:
Yeast   354 KSVGMN-DSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPN 417

  Fly   359 ---GPDVSHLG--WLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFV 418
               .|.....|  .:..|||  ||..||..:||:.::::.|..|.::|....||.||.|....|:
Yeast   418 GKSEPSSKGAGNCTIVFTCF--YIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFL 480

  Fly   419 VTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMM-GRVPMSS 477
            :......:|.|:..:..:...|.:.. ..|:|..|||||:|.:|||::...| |.:|..|
Yeast   481 IGFFTPFITSAINFYYGYVFMGCLAF-SYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	MFS_GLUT6_8_Class3_like	29..464	CDD:340916	117/467 (25%)
HXT8	NP_012321.1	Sugar_tr	69..530	CDD:395036	117/465 (25%)