Protein Alignment Tret1-2 and hmit-1.3

DIOPT Version :10

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 153/550 - (27%)
• Similarity: 242/550 - (44%)
• Gaps: 122/550 - (22%)

  Fly    35 VSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGS-W---VGGIMPLAALAGGITGGPLIEY 95
            ::..:::.||:..|.: .:||.....:.:....|...| |   :..|.|..|..|.:..||..::
 Worm    31 LAFSAVIGGFLFGYDT-GIVSAAMLYVPNASGIKPLDSVWQEIIVSITPGVAAIGSLCSGPGSDF 94

  Fly    96 LGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRG--- 157
            |||:..|:..:|.|.:.:::.|.|...|::|.||.|.|..:|.||:.:|:|:.|.....:||
 Worm    95 LGRKKIIIGASVTFTIGAIICAAAWTKIILLIGRILLGLAIGFASMIVPIYVSEASPSHIRGKLV 159

  Fly   158 -------TLGLLPTALGN-IGILVCYVAGSFMNWSMLAFLGAALP--VPFLILMIIIPETPRWFV 212
                   |:||:   :.| ||....||....:.|.:: |..||:|  :.| :..:.:||:|||..
 Worm   160 TGFQLMITVGLV---IANIIGGAFSYVDPDQVGWRLM-FAFAAVPAIIQF-VCFLFLPESPRWLY 219

  Fly   213 NRGQEERARKAL-KWLRGKEADVEPELKELMQS-----QADADRQATQNTCLELFKRNNL-KPLS 270
            ..|:...||:.| :...|....|:.|:.|:..|     :|.|:......|.:.:.|..:: |.:.
 Worm   220 EHGRTVEAREVLTRIYNGHTEWVDYEINEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMI 284

  Fly   271 ISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGV----VNFFATFMGIILIDRLGR 331
            |...|..|||.||||.|::||..|.:.||  :..|.:||.:.|    :||..||:.|.|::|:||
 Worm   285 IGSLLQMFQQLSGINTVMYYTGNIIRSAG--VKDNHTTIWISVGTSAINFLGTFIPIALVERVGR 347

  Fly   332 KILLYVSDIAMIVTLSILGGFF---------------YCKAHGPDVSHLG--------------- 366
            ::||.||.|.:|:.|..:|..|               |...:.|.|.|..
 Worm   348 RVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDE 412

  Fly   367 ---------------------------------------------W-----------LPLTCFVI 375
                                                         |           ||:...|.
 Worm   413 NCGFCESKVAKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTDFEWEDTYCHTKFTVLPIIIMVF 477

  Fly   376 YILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFG 440
            |:|.||.|:.|:||::..|..|...|..|.||.||.||....:|:.||..|:.|...:|.|:::.
 Worm   478 YLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYC 542

  Fly   441 AICIVGLFFVIIFVPETRGKSLEEIERKMM 470
            ...:|.|.||..|||||:|.|::|:|...|
 Worm   543 GCTMVALVFVFFFVPETKGYSIDEVEMLFM 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	MFS_GLUT6_8_Class3_like	29..464	CDD:340916	150/542 (28%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:475125	145/531 (27%)
		MFS	<190..>249	CDD:475125	18/60 (30%)