DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and slc2a13

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_004913061.2	Gene:	slc2a13 / 100485871	XenbaseID:	XB-GENE-492054	Length:	646	Species:	Xenopus tropicalis

Alignment Length:	538	Identity:	139/538 - (25%)
Similarity:	230/538 - (42%)	Gaps:	107/538 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 VSLCSLVVGFVSAY-----TSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIE 94
            ||:.|.:.||:..|     :...|:...:..:::........|.||. ..|:|||||:..|
Frog    82 VSVFSALGGFLFGYDTGVVSGAMLLLKREMNLSALWQELLVSSTVGA-AALSALAGGVLNG---- 141

  Fly    95 YLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTL 159
            .||||..||..::.|...::::|.|.:...:|.||.:.|..:||||:::|||:.|...|.:||.|
Frog   142 VLGRRPCILMASLLFTAGAVILAAARDKETLLGGRVVVGLGIGIASMTVPVYIAEAAPPHLRGRL 206

  Fly   160 GLLPTAL---GNIGILVCYVAGSFM---NWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEE 218
            ..:.|..   |.....|...|.|::   .|..:..|.|...|...:..:.:||:|||.:.:||.:
Frog   207 VTINTLFITGGQFSAAVVDGAFSYLARDGWRYMLGLSAVPAVLQFLGFLFLPESPRWLIQKGQTQ 271

  Fly   219 RARKALKWLRGKEADVEPELKELMQSQADADRQ-ATQNTCL--ELFKRNNLKPLSISLGLMFFQQ 280
            :||:.|..:||.:. ::.|...:..|..:.::: ||....:  .|......:.|.:..||..|||
Frog   272 KARRVLSQIRGNQT-IDEEYDSIKNSIDEEEKEGATGGPIIYRMLIYPPTRRALIVGCGLQMFQQ 335

  Fly   281 FSGINAVIFYTVQIFKDAGSTIDSNLSTI----IVGVVNFFATFMGIILIDRLGRKILLYVSDIA 341
            .:|||.|::|:..|.:.:|  :|.:...|    :....||..|.:|:.|:::|||:.|...|...
Frog   336 LAGINTVMYYSATILQMSG--VDDDRLAIWLAAVTAFTNFSFTLLGVWLVEKLGRRKLTLGSLTG 398

  Fly   342 MIVTLSILG-GFF---------------------------YC-------------KAHGPDV--- 362
            ..|.|.:|. ||.                           ||             |.:|..:
Frog   399 TTVALFVLALGFLLSAQVSPPVTFTPGDPSGPNSTCTQYSYCNKCMLDPNCGFCYKKNGSSIVDS 463

  Fly   363 -------------------------------------SHLGWLPLTCFVIYILGFSLGFGPIPWL 390
                                                 :...|..|...::|::.|:.|.||:||.
Frog   464 SCIPVNTESTDRAAWGRCMNETKSKAGGSIWAYNYCPTSYSWTALLGLILYLVFFAPGMGPMPWT 528

  Fly   391 MMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVP 455
            :..||.|...|....:..:..||.|..:::.||......:..:|||:|:..:..|||.|:...:|
Frog   529 VNSEIYPLWARSTGNACSSGVNWICNVLISLTFLHTAEYLTYYGAFFLYAGLACVGLIFIYGCLP 593

  Fly   456 ETRGKSLEEIERKMMGRV 473
            ||:||.|||||.....|:
Frog   594 ETKGKKLEEIESLFESRL 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	137/530 (26%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	128/517 (25%)
slc2a13	XP_004913061.2	MFS_HMIT_like	85..594	CDD:340918	126/516 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010