DRSC/TRiP Functional Genomics Resources

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Protein Alignment Egm and ACADS

DIOPT Version :10

Sequence 1:NP_610687.1 Gene:Egm / 36242 FlyBaseID:FBgn0086712 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_000008.1 Gene:ACADS / 35 HGNCID:90 Length:412 Species:Homo sapiens


Alignment Length:401 Identity:96/401 - (23%)
Similarity:162/401 - (40%) Gaps:57/401 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 ESVEESPEQQRKLPT-REPLAKNFF--IGVVDKELLAYPEVIPRDEMAQLENSLLPLKNYFVEPR 112
            :|||.....|..|.| |:...|..|  ...||||.| :|       .||::.             
Human    30 QSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHL-FP-------AAQVKK------------- 73

  Fly   113 ETEETSPETLRQLGLYGLNVSTDYEGKGYGWSASLMASEPDS---TDINVTLGLQTHRVVVDLLK 174
                     :..|||..::|..:..|.|..:.|..:|.|..|   ....|.:.:.....:..:||
Human    74 ---------MGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILK 129

  Fly   175 EVGTPLQQQRYLQDLATGKLIGTEAIYEISPP----EEDYFNTTAELFPEYGKWQLNGEKSFVIC 235
             .|:..|:|.::....:|..||   .:.:|.|    :....:|||.  .|...|.|||.|:: |.
Human   130 -FGSKEQKQAWVTPFTSGDKIG---CFALSEPGNGSDAGAASTTAR--AEGDSWVLNGTKAW-IT 187

  Fly   236 TPGERQLFLVLAQTQQPNVPGVLGRGTTIFLVDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVKL 300
            ...|....:|.|.|.:    .:..:|.:.|||.....|:.||:|....|.|.:....:.||..::
Human   188 NAWEASAAVVFASTDR----ALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRI 248

  Fly   301 GEDQVVGLPHDGNRYSEQLVRSSRLRGSLVGLSLAKKLLNELAQYTVNTTQCGVQLQDLELTRIH 365
            .:|.::|.|..|.:.:.|.:...|:..:...|.:|:..|:....|..|....|..|..|::.:..
Human   249 PKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFK 313

  Fly   366 MSRAMCSVYAMESMLYLT--AGLLDEFRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLS 428
            ::.   ...|:||...||  |.:|.:.:...:. |:|:.|........||:.|.:.::|....::
Human   314 LAD---MALALESARLLTWRAAMLKDNKKPFIK-EAAMAKLAASEAATAISHQAIQILGGMGYVT 374

  Fly   429 GETTELGLRDA 439
            ....|...|||
Human   375 EMPAERHYRDA 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EgmNP_610687.1 ACAD 92..457 CDD:173838 81/357 (23%)
ACADSNP_000008.1 SCAD_SBCAD 36..408 CDD:173847 93/395 (24%)

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