Protein Alignment Egm and Acadvl

DIOPT Version :10

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_037023.1
• Gene: Acadvl / 25363
• RGDID: 2014
• Length: 655
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 165/664 - (24%)
• Similarity: 293/664 - (44%)
• Gaps: 68/664 - (10%)

  Fly    19 GKLLTRGRSTKATSSSLDSQHQDAATTE---GGRAESVEESPE------QQRKLPTREPLAKNFF 74
            |:.|.|..:..:.|::|..|.:..:...   ....::|.|.||      ..|:.|.|.. :|:|.
  Rat    11 GRQLLRLGARSSRSAALQGQPRPTSAQRLYASEATQAVLEKPETLSSDASTREKPARAE-SKSFA 74

  Fly    75 IGVVDKEL-----LAYPEVIPRDEMAQLENSLLPLKNYFVEPRE---------TEETSPETLRQL 125
            :|:...:|     ..||.|:...:...|:..:.|:..:|.|..:         .||.:.:.|::|
  Rat    75 VGMFKGQLTTDQVFPYPSVLNEGQTQFLKELVGPVARFFEEVNDPAKNDSLEKVEEDTLQGLKEL 139

  Fly   126 GLYGLNVSTDYEGKG-----YGWSASLMASEPDSTDINVTLGLQTHRVVVDLLKEV---GTPLQQ 182
            |.:||.|.::..|.|     |...|.::...    |:.|::.|..|:.:.  .|.:   ||..|:
  Rat   140 GAFGLQVPSELGGLGLSNTQYARLAEIVGMH----DLGVSVTLGAHQSIG--FKGILLYGTKAQK 198

  Fly   183 QRYLQDLATGKLIGTEAIYEISPPEEDYFNTTAELFPE-YGK-WQLNGEKSFVICTPGERQLFLV 245
            ::||..:|:|:.:....:.|.| ...|..:..:...|. .|| :.|||.|.: |...|...:|.|
  Rat   199 EKYLPRVASGQALAAFCLTEPS-SGSDVASIRSSAVPSPCGKYYTLNGSKIW-ISNGGLADIFTV 261

  Fly   246 LAQTQ-QPNVPGVLGRGTTIFLVDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVKLGEDQVVGLP 309
            .|:|. :....|.:....|.|:|:....||..|......|.:.:....|:|:|||:..:.|:|..
  Rat   262 FAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPAENVLGEV 326

  Fly   310 HDGNRYSEQLVRSSR--LRGSLVGLSLAKKLLNELAQYTVNTTQCGVQLQDLELTRIHMSRAMCS 372
            .||.:.:..::.:.|  :..:|.|  ..|.::.:...:..|.||.|.::.:..:.:..::|....
  Rat   327 GDGFKVAVNILNNGRFGMAATLAG--TMKAIIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAIL 389

  Fly   373 VYAMESMLYLTAGLLDE-FRAQDVTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTELGL 436
            .|..|||.|:.:..:|: |:  |..:|:||:|.|.....:.:..:.:.::|....:.....|..|
  Rat   390 QYVTESMAYMLSANMDQGFK--DFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452

  Fly   437 RDAAQLCTQGESLDTLGMFIALTGLQHAGQAMNTGVRKS-RNPLFNPGHIFG---KFLDNNSIDN 497
            ||.........:.|.|.:|:||.|....|:.: ||:..: :|||.|.|.:.|   |.|...:  .
  Rat   453 RDIRIFRIFEGTNDILRLFVALQGCMDKGKEL-TGLGNALKNPLGNVGLLIGEASKQLRRRT--G 514

  Fly   498 PKTKMQLSEHVHPSLEAAAQCIELSVARLQMAVELMFTKHGNAVVERQSEMQRLAEVGTLIYAMW 562
            ..:.:.||..|||.|..:.:....::.:....||....||...:|..|..:||||:....:|||.
  Rat   515 IGSGLSLSGIVHPELSRSGELAVQALEQFATVVEAKLMKHKKGIVNEQFLLQRLADGAIDLYAMV 579

  Fly   563 ASVARASRSYCIGLPLADHELLTATAICSEGRDRVRTLCTEIYGGHFVNND------NNLVRLSK 621
            ..::|||||...|.|.|.||.:...:.|.|...|:|.....:.     :|.      .|...:||
  Rat   580 VVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQ-----SNPQQQELFRNFRSISK 639

  Fly   622 QVAKSKGYFAVHPL 635
            .:.::.|....:||
  Rat   640 AMVENGGLVTSNPL 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	91/387 (24%)
Acadvl	NP_037023.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70		13/59 (22%)
		Catalytic. /evidence=ECO:0000250|UniProtKB:P49748	41..482		108/453 (24%)
		VLCAD	72..481	CDD:173850	100/420 (24%)
		Membrane-anchoring. /evidence=ECO:0000250|UniProtKB:P49748	483..516		10/35 (29%)