Protein Alignment Egm and acdh-12

DIOPT Version :10

• Sequence 1: NP_610687.1
• Gene: Egm / 36242
• FlyBaseID: FBgn0086712
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001022062.1
• Gene: acdh-12 / 174180
• WormBaseID: WBGene00017125
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 153/643 - (23%)
• Similarity: 263/643 - (40%)
• Gaps: 61/643 - (9%)

  Fly    21 LLTRGRSTKATSSSLDSQHQDAATTEGGRAESVE--ESPEQQRKLPTREPLAKNFFIG-VVDKEL 82
            |.|..:|.:...:........||..:..:.:.|.  :||.          ...|.|.| .|..::
 Worm     2 LSTLSKSARLNQTRFIRLSHSAAAAKDAKPKKVAAVDSPS----------FVMNLFRGKAVTDQV 56

  Fly    83 LAYPEVIPRDEMAQLENSLLPLKNYFVEPRE---TEETSP------ETLRQLGLYGLNVSTDYEG 138
            ..||..:..::...|...:.||:...||..:   .:|||.      :...:||.:|:.|..:.||
 Worm    57 FPYPLNMTDEQKETLGMVMSPLEKMLVEVNDVVKNDETSDIPRAVLDQFAELGTFGVLVPPELEG 121

  Fly   139 KGYGWSASLMASE-PDSTDINVTLGLQTHRVV--VDLLKEVGTPLQQQRYLQDLATGKLIGTEAI 200
            .|:..|.....:| ..:.|:...:.:..|:.:  ..:|.| ||..|:|:||.|||||:.....|:
 Worm   122 SGFNNSQMARVAEIVGAYDLGFGVVMGAHQSIGYKGILLE-GTDAQKQKYLPDLATGRKFAAFAL 185

  Fly   201 YE-ISPPEEDYFNTTAELFPEYGKWQLNGEKSFVICTPGERQLFLVLAQTQQPNVPGVLGRGTTI 264
            .| .:..:.....|.|||..:...:.|||.|.: |...|...:|.|.|||......|......:.
 Worm   186 TEPTTGSDASSVRTRAELSADGKHYVLNGGKIW-ISNGGFADVFTVFAQTPVKQADGSTKDKMSA 249

  Fly   265 FLVDSQQEGVRLGEKHATFGCRKAEIRRVHFEGVKLGEDQVVGLPHDGNRYSEQLVRSSRLRGSL 329
            |:|:....||..|.:....|.:.:....|||:.:|:..:.::|...:|.:.:..::.:.|.....
 Worm   250 FIVERAFGGVTSGPQEKKMGIKGSNTTEVHFDNLKIPVENLLGKEGEGFKVAMNILNNGRFGIPA 314

  Fly   330 VGLSLAKKLLNELAQYTVNTTQCGVQLQDLELTRIHMSRAMCSVYAMESMLYLTAGLLDEFRAQD 394
            ......|..:.:...:.....|.|.:||:....:..:...:..:||.||::|:.:..:|. ..::
 Worm   315 ACTGAMKHCIQKTVDHITTRVQFGKKLQEFGNIQEKLVEMISKLYATESIVYMLSSNMDR-GIKE 378

  Fly   395 VTLESAITKYFTLRQVYAIASQNLGVVGPKSLLSGETTELGLRDAAQLCTQGESLDTLGMFIALT 459
            ..||:||.|.......:.:....:.|.|....:.....|..|||.........:.|.|.:|||||
 Worm   379 YQLEAAIGKVLASENAWLVCDDAIQVHGGMGFMRETGLERVLRDLRIFRIFEGANDVLRLFIALT 443

  Fly   460 GLQHAG-----QAMNT----GVRKSRNPLFNPGHIFGKFLDNNSIDNPKTKMQLSEHVHPSLEAA 515
            |.||||     ||...    |:..||....|.|..||:.:|                  .||:.:
 Worm   444 GAQHAGKHLAEQASGVGGLIGLAVSRVTGGNTGSNFGQVVD------------------ASLQDS 490

  Fly   516 AQCIELSVARLQMAVELMFTKHGNAVVERQSEMQRLAEVGTLIYAMWASVARASRSYCIGLPLAD 580
            |:.::..:|.....|:.:..||...:::||.||.|:|:....||:..|.::||:.:.......||
 Worm   491 AKVLDQQIALFGQTVQGLLMKHKKGIIDRQYEMHRVADAAINIYSSAAVLSRATYAIKNKSSSAD 555

  Fly   581 HELLTATAICSEGRDRVRTLCTEIYGGHFVNNDNNLV---RLSKQVAKSKGYFAVHPL 635
            .|...||....:..........:  .|..|.|.:.:.   .|:|:|..:.|....||:
 Worm   556 FERKVATYYVDKAMKSSNRFLKD--AGSGVENASKVATIESLAKEVCGNGGLTLQHPV 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Egm	NP_610687.1	ACAD	92..457	CDD:173838	88/377 (23%)
acdh-12	NP_001022062.1	VLCAD	41..449	CDD:173850	101/420 (24%)