Protein Alignment en and cad

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 73/297 - (24%)
• Similarity: 117/297 - (39%)
• Gaps: 73/297 - (24%)

  Fly   318 PLSSSASSLASPPPASNASTI-------SSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGS 375
            |.||:|.:.....|.|....:       :..||.:.||.|||||.:..|..||.:.|| :|..|:
  Fly    86 PASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSS-IGVGGA 149

  Fly   376 ------------GVNASSPQPQ-------PIPP-------------PSAVS-------------- 394
                        |..::.|..|       |.||             |::.|
  Fly   150 GGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVA 214

  Fly   395 ----RDSGMESSDDTRSETGSTTTEGGKNEMWPA------WVYCTRYSDRP----SSGPRYRRPK 445
                .::...:|..|.:...:..:....|...|:      |:....|..:|    ||.|......
  Fly   215 NNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLS 279

  Fly   446 QPKD---KTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRA 507
            ...|   ||..:.:.|..::..|...|::|:..:||:|.||:.:|:..|.|:|.|:||||||:||
  Fly   280 DLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRA 344

  Fly   508 KIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELE 544
            |.:|.  :|......:|..|:.:.....|...:.:||
  Fly   345 KERKQ--NKKGSDPNVMGVGVQHADYSQLLDAKAKLE 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	512..542	CDD:431338	4/29 (14%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)