Protein Alignment en and dlx2b

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_571372.1
• Gene: dlx2b / 30557
• ZFINID: ZDB-GENE-980526-18
• Length: 276
• Species: Danio rerio
• Alignment Length: 214
• Identity: 67/214 - (31%)
• Similarity: 100/214 - (46%)
• Gaps: 40/214 - (18%)

  Fly   320 SSSASSL--ASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSP 382
            |||.|::  :...|....||::.:|..   |||.:..|:..|.:..:|.|...|..|: |:.|
Zfish    19 SSSFSTVHKSQDSPTLPVSTVTDSSFF---SSSQTGHCAGTAYAQLASYSYHPGTVGN-VHYS-- 77

  Fly   383 QPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYR----R 443
                   |.|.  |.|..||      .|:..|.|..:...|.      ..::..|.|..|    :
Zfish    78 -------PKAY--DLGYASS------YGAYGTYGASSSPTPT------EPEKEESEPEVRMVNGK 121

  Fly   444 PKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAK 508
            ||:       .::|||.:||.|||.|:|.|.:.:||....|.:|::.|||.:.|:||||||:|:|
Zfish   122 PKK-------VRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSK 179

  Fly   509 IKKSTGSKNPLALQLMAQG 527
            .||...:....|.|.:|.|
Zfish   180 FKKLWKNGEIPADQQVASG 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	512..542	CDD:431338	4/16 (25%)
dlx2b	NP_571372.1	DLL_N	29..102	CDD:463567	24/93 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	97..123		4/31 (13%)
		Homeodomain	126..182	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	191..238		4/8 (50%)