Protein Alignment en and Dbx1

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001005232.1
• Gene: Dbx1 / 13172
• MGIID: 94867
• Length: 335
• Species: Mus musculus
• Alignment Length: 321
• Identity: 79/321 - (24%)
• Similarity: 122/321 - (38%)
• Gaps: 84/321 - (26%)

  Fly   254 PAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPP 318
            ||.||         .|.|......:|..:.|..|..:      ..|.:.:.:|.:|  ||.
Mouse    10 PAGYP---------SLLRPTPTLTLPQSLQSAFSGHS------SFLVEDLIRISRP--PTY---- 53

  Fly   319 LSSSASSLASPPPASNASTI---SSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNA- 379
            ||.|..:.:..||:..|...   |.||.:.:..|.|..| ||..::|  ||:|.......||||
Mouse    54 LSRSIPAASLSPPSQEAPAALADSGTSDLGSPGSGSRRG-SSPQTAL--SPASEPTFLKFGVNAI 115

  Fly   380 --------SSPQPQPIPPPSAVS------------RDSGMESSDDTRSETGSTTTEGGKNEMWPA 424
                    :||.....|||...:            |.|...:|.......|:.:        ||.
Mouse   116 LSSAPRRETSPALLQSPPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFS--------WPL 172

  Fly   425 WVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSS 489
                                 ..:.|.......|..||..|...|::.|.:.:|:::..|::|:|
Mouse   173 ---------------------AARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLAS 216

  Fly   490 ELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQ 550
            :|||.::|:||||||:|.|      .:|....:|::.|.....|:| ||.....::...||
Mouse   217 KLGLKDSQVKIWFQNRRMK------WRNSKERELLSSGGCREQTLP-TKLNPHPDLSDVGQ 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	22/55 (40%)
		Engrail_1_C_sig	512..542	CDD:431338	7/29 (24%)
Dbx1	NP_001005232.1	PRK12323	<49..182	CDD:481241	37/170 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..102		13/46 (28%)
		Homeodomain	184..238	CDD:459649	22/59 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..335		8/32 (25%)