Protein Alignment en and unpg

DIOPT Version :10

• Sequence 1: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_308835.5
• Gene: unpg / 1270160
• VectorBaseID: AGAMI1_008945
• Length: 588
• Species: Anopheles gambiae
• Alignment Length: 588
• Identity: 126/588 - (21%)
• Similarity: 174/588 - (29%)
• Gaps: 237/588 - (40%)

  Fly     7 CSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAA 71
            |||.:|...:......|..:..||||||.|..:|                           ||||
Mosquito    65 CSPPAAGPNVPPGYGSLLLETSQQQQQQHQQHYL---------------------------AAAA 102

  Fly    72 AAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEE 136
            ||..:||..:.:....|..       |.|...|.:...|:   :.::..:..:.||:.:...|:
Mosquito   103 AAGYSAAMLSFSSFPPLYH-------PWSTGLPTAGRYLS---QAANEKLSSLLFHHHSSGGNK- 156

  Fly   137 EEAEEDDDIDVDVDDTSAGGRLP-----PPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSME 196
                           :..||..|     |.|.|.||.....|....|:....|.||...|
Mosquito   157 ---------------SHPGGIEPCPGTYPAAEQPQSGGGGVLPTRPSSPRGARSGDKLFP----- 201

  Fly   197 NQASIFRPFEASRSQTATPSAFTRVDLLE-----FSRQQQ---------------AAAAAATAAM 241
                                  |.||||.     :..|||               ......|...
Mosquito   202 ----------------------TEVDLLSKVYAVYHHQQQQQQQQQQPRYLTPSSPGTGYTTTGA 244

  Fly   242 MLERANFLNCFNP-AAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQ 305
            .||.    |..|| ....::|.:      .:|....:.|.      ||..||..
Mosquito   245 ALEP----NGVNPGTGNGQLHHQ------PQSPGETIDPG------SDGGPEDE----------- 282

  Fly   306 IGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSS----------SSSSGCSSAAS 360
                   ..|:|.:.....|       ::.|..|...|:..|.|          |.|..||....
Mosquito   283 -------ERTRPTIEDGGES-------ADGSAYSDDISLTLSPSGCGKTTDLGDSDSDACSEDDC 333

  Fly   361 SLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAW 425
            :.|||.|.|.|.||||...|.
Mosquito   334 TQNSSSSGRAGKSGSGAENSK-------------------------------------------- 354

  Fly   426 VYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSE 490
                                        .:|.||||:||||..|:|||:..:||:...|.|:::.
Mosquito   355 ----------------------------SRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATS 391

  Fly   491 LGLNEAQIKIWFQNKRAKIKK--------STGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRM 547
            |.|:|.|:||||||:|||.|:        ..|::|.........|..|...||:........:|.
Mosquito   392 LKLSEVQVKIWFQNRRAKWKRVKAGLNSHGLGNRNASGSGTGTTGTANKIVVPIPVHVNRFAIRS 456

  Fly   548 NGQ 550
            ..|
Mosquito   457 QHQ 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
en	NP_523700.2	Homeodomain	455..511	CDD:459649	30/55 (55%)
		Engrail_1_C_sig	512..542	CDD:431338	6/29 (21%)
unpg	XP_308835.5	None