Protein Alignment inv and BARX2

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 46/163 - (28%)
• Similarity: 69/163 - (42%)
• Gaps: 24/163 - (14%)

  Fly   433 RSPRARKPKKPAT--------------SSSAAGGGGGGVEKGEAADGGGVPEDKRP---RTAFSG 480
            |.|.......|||              :.||...||..:...|:......|..|:|   ||.|:.
Human    78 RQPTVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTE 142

  Fly   481 TQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK---SSGTKNPLALQLMA 542
            .||..|:.:|.:.:||:...|..|:..|||.:.|:|.|:||:|.|.||   ..|.:.|    ...
Human   143 LQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAP----TKP 203

  Fly   543 QGLYNHSTIPLTREEEELQELQEAASAAAAKEP 575
            :|....::||.:.|.|..:::...|......||
Human   204 KGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEP 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/58 (40%)
		Engrail_1_C_sig	529..554	CDD:431338	5/24 (21%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		6/26 (23%)
		Homeodomain	134..190	CDD:459649	21/55 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		10/47 (21%)