Protein Alignment inv and Nkx6-3

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001102925.1
• Gene: Nkx6-3 / 685102
• RGDID: 1597780
• Length: 262
• Species: Rattus norvegicus
• Alignment Length: 223
• Identity: 54/223 - (24%)
• Similarity: 85/223 - (38%)
• Gaps: 59/223 - (26%)

  Fly   340 NLAQSNAAANSSLS-FSSSLANICSNSNDSN-------------STATSSSTTNTSGAPV----- 385
            ||..:....|:.|: ||...|.:|..|..::             :..|....|:....||
  Rat     4 NLQGTFLLNNTQLAQFSEMKAPMCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVATPNS 68

  Fly   386 DLVKSPPPAAGAGATGASG-----------KSGED--SGTPIVWPAWVYCTRYSDRPSSGRSPRA 437
            .|:...|..||.|...:.|           |:|.:  :.|...|.......|.|.||.| .:|
  Rat    69 SLLSGYPHVAGFGGLSSQGVYYGPQVGSFSKTGNEYPTRTRNCWADTGQDWRGSTRPCS-NTP-- 130

  Fly   438 RKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQ 502
                .|.:.:                    :.:.|..|..|:|.|:..|:..|.:.:||....|.
  Rat   131 ----DPLSDT--------------------IHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERA 171

  Fly   503 QLSGELGLNEAQIKIWFQNKRAKLKKSS 530
            :|:..||:.|:|:|:||||:|.|.:|.|
  Rat   172 RLAYSLGMTESQVKVWFQNRRTKWRKKS 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	22/55 (40%)
		Engrail_1_C_sig	529..554	CDD:431338	1/2 (50%)
Nkx6-3	NP_001102925.1	Homeodomain	139..197	CDD:459649	22/57 (39%)