Protein Alignment inv and Vax1

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_072158.1
• Gene: Vax1 / 64571
• RGDID: 621132
• Length: 336
• Species: Rattus norvegicus
• Alignment Length: 197
• Identity: 57/197 - (28%)
• Similarity: 78/197 - (39%)
• Gaps: 56/197 - (28%)

  Fly   369 NSTATSSSTTNTSGA-PVDLVKSPPPAAGAGATGASGKSGED--------SGTPIVWPAWVYCTR 424
            |:...|.......|: |...:|.|     .||..|||.| ||        |..|      .||.|
  Rat    24 NAHKESREIKGAEGSLPAAFLKEP-----QGAFSASGAS-EDCNKSKSNSSADP------DYCRR 76

  Fly   425 YSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHE 489
            ...|.:.|.......||                       |..:...||.||:|:..||.||:.|
  Rat    77 ILVRDAKGSIREIILPK-----------------------GLDLDRPKRTRTSFTAEQLYRLEME 118

  Fly   490 FNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPL------------ALQLMA 542
            |...:|:..:.|.:|:.:|.|:|.|:|:||||:|.|.||..|..:.|            .|:|:.
  Rat   119 FQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLE 183

  Fly   543 QG 544
            ||
  Rat   184 QG 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	529..554	CDD:431338	6/28 (21%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		3/14 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..69		7/19 (37%)
		vax upstream domain	72..99		8/49 (16%)
		homeobox	100..159		27/58 (47%)
		Homeodomain	101..157	CDD:459649	25/55 (45%)
		vax downstream domain	178..189		4/8 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..267
		vax terminal domain	315..323