Protein Alignment inv and nkx6.2

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001129256.1
• Gene: nkx6.2 / 565782
• ZFINID: ZDB-GENE-070626-1
• Length: 278
• Species: Danio rerio
• Alignment Length: 341
• Identity: 73/341 - (21%)
• Similarity: 117/341 - (34%)
• Gaps: 116/341 - (34%)

  Fly   223 GQDALAQLTATALGLGPGGAVHPHQQLLLQRDQVHHHHHMQNHLNNNENLHERALKFSI-DNILK 286
            ||....:.:|..||..|..|:|                          |:.|  :|.|: ...|:
Zfish     5 GQMDSNRQSAFVLGSTPLAALH--------------------------NMTE--MKTSLFPYALQ 41

  Fly   287 ADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSS 351
            :..|.:.|.:|.|:..|..|:..|.|                    ...|:|:..|
Zfish    42 SPAGFKAPSLGNLNSQIPLGTPHGIS--------------------DILGRPITTA--------- 77

  Fly   352 LSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDSGTPIVW 416
                   ..:.|.....|..|||:.....   |..:.:.|.|     .|...|::      ||.|
Zfish    78 -------GQLLSGFPRINGLATSAGMYFN---PAAVSRYPKP-----LTELPGRA------PIFW 121

  Fly   417 PAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGT 481
            |..:..:.:.|            |:.|..:           :.....|..|..:..||  .|||.
Zfish   122 PGMMQGSPWRD------------PRVPCAA-----------QANMMLDKDGKKKHSRP--TFSGQ 161

  Fly   482 QLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLY 546
            |:..|:..|.:.:||....|.:|:..||:.|:|:|:||||:|.|.:|....:       ||....
Zfish   162 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAE-------MATAKK 219

  Fly   547 NHSTIPLTREEEELQE 562
            .|.:     |.|:::|
Zfish   220 KHDS-----ETEKMKE 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	3/24 (13%)
nkx6.2	NP_001129256.1	Homeodomain	150..208	CDD:459649	23/59 (39%)