Protein Alignment inv and HGTX

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 130/585 - (22%)
• Similarity: 191/585 - (32%)
• Gaps: 262/585 - (44%)

  Fly   118 AQAQARQRLLISQIYRPSAFSSTATTVLPPS--EGPP-----------FSPE-DLLQ-------- 160
            |:..|:|   ::|.::.|| :|.....|||:  ..||           .:|| ||:.
  Fly    27 AKVAAKQ---LAQSFQLSA-NSAFNLALPPAFYRAPPQQHPECLDYGHEAPEMDLINPYMRHHSF 87

  Fly   161 ------LPPSTGTFQEEFLRKSQLYAEELMKQQMHLMAA-----ARVNALTAAAAGKQLQM---- 210
                  .|||..                   |:.||.||     |.|:|...|||..|.|:
  Fly    88 AAAAQGSPPSAA-------------------QRHHLAAAMSNGFADVHAHAMAAADYQQQLADYH 133

  Fly   211 -AMAAAAV--------------------------------------ATVP--------------- 221
             |.|||||                                      :|.|
  Fly   134 SAAAAAAVYANNNNNNNNNSSNNNNSSPLMLLKAAHGGGLKDSDSPSTTPPPASSRLHSDSSPSP 198

  Fly   222 ----SGQDALAQLTATALGLGPGGAVHPHQ------------------QLLLQRDQVHHHH---- 260
                :....:....:.||.....||..|.|                  .|..||.:..|||
  Fly   199 RYEHNSSPGVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNP 263

  Fly   261 ---HMQNHLNN----NENLHERALKFSIDNILKADF-GSRLPKIGALSGNIGGGSVSGSSTGSSK 317
               |..||..|    |.|.|       :|:.|...| |..|..:.:::..:.|..|.|||
  Fly   264 LALHNANHAGNPGCHNNNNH-------MDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSS----- 316

  Fly   318 NSGNTNGNRSPLKAPKKSGKPLNLAQSNAAANSSLSFS----SSLANICSNSNDSNSTATSSSTT 378
                                        |:|| .||:|    |.|.:...:...|:|::|:::.|
  Fly   317 ----------------------------ASAN-GLSYSHSPNSHLISDRGSGGSSSSSSTTTTNT 352

  Fly   379 NTSGAP----VDLVKS-PPPAAGAG--------------ATGASGKS---GEDSGTP-------- 413
            |:.|||    :|.:.| |||...||              |..|:|.:   .:..|.|
  Fly   353 NSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHI 417

  Fly   414 -----IVWP----------AWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAA 463
                 :.||          ||      .:|.|:..|....:..:...|:...|
  Fly   418 VDRTHLYWPGLQGLVANPIAW------RERLSNTMSANLSQSHQHHPSNDKDG------------ 464

  Fly   464 DGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK 528
                  :.|..|..|||.|:..|:..|.:.:||....|.:|:..||::|:|:|:||||:|.|.:|
  Fly   465 ------KKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRK 523

  Fly   529  528
              Fly   524  523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	130/585 (22%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	54/249 (22%)
		Homeodomain	465..523	CDD:459649	23/57 (40%)