Protein Alignment inv and hoxd3a

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_571200.1
• Gene: hoxd3a / 30349
• ZFINID: ZDB-GENE-990415-120
• Length: 396
• Species: Danio rerio
• Alignment Length: 277
• Identity: 74/277 - (26%)
• Similarity: 107/277 - (38%)
• Gaps: 89/277 - (32%)

  Fly   273 HERALKFSIDNILKADFGSRLPKIGALS---GNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAPKK 334
            |:.....||:|    |:.|.:..|...|   .....|.::||....|.:.||:
Zfish    30 HQGFSSSSIEN----DYQSPICPIQTTSVRQATHKNGDINGSCMRPSASQGNS------------ 78

  Fly   335 SGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGA 399
              :|.::::...||..:.|         |.|..:|||...              |||
Zfish    79 --QPESISEQQQAAPLAAS---------SPSPSTNSTQKK--------------KSP-------- 110

  Fly   400 TGASGKSGEDSGTPI----VWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKG 460
                ..:|..:.||:    ::| |:..||.:.:..|...|.|                      |
Zfish   111 ----SSNGSSTATPVISKQIFP-WMKETRQNAKQKSTNCPAA----------------------G 148

  Fly   461 EAADGGGV--PEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKR 523
            |..|....  |..||.|||::..||..|:.||:.||||...||.:::..|.|.|.||||||||:|
Zfish   149 ETCDDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 213

  Fly   524 AKLKKSSGTK----NPL 536
            .|.||...:|    :||
Zfish   214 MKYKKDQKSKGIMHSPL 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	29/55 (53%)
		Engrail_1_C_sig	529..554	CDD:431338	3/12 (25%)
hoxd3a	NP_571200.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..163		40/208 (19%)
		COG5576	116..237	CDD:227863	47/138 (34%)
		Antp-type hexapeptide	126..131		2/5 (40%)
		Homeodomain	162..218	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..246		3/12 (25%)
		DUF4074	333..394	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..396