Protein Alignment inv and hoxb2a

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_571191.1
• Gene: hoxb2a / 30338
• ZFINID: ZDB-GENE-990415-103
• Length: 390
• Species: Danio rerio
• Alignment Length: 254
• Identity: 68/254 - (26%)
• Similarity: 108/254 - (42%)
• Gaps: 51/254 - (20%)

  Fly   350 SSLSFSSSLANICSNSNDSNSTAT-------SSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSG 407
            ||:..|:::.....::..|.|..|       |...|.::|..:....:||.....|....||
Zfish    35 SSIKDSTAIPPPFEHTIPSLSPCTGNQARPRSQKRTASNGLQLRTQTAPPTQHQQGPAPLSG--- 96

  Fly   408 EDSGTPIV--WPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGG---GGVEKGEAADGG- 466
               |.|:.  :| |:     .::.||.:.|:.......|.:|.:....|   .|:|......||
Zfish    97 ---GAPLAHEFP-WM-----KEKKSSKKCPKPGATAAAAAASPSQASSGYTTAGLESPTEIQGGL 152

  Fly   467 -GVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSS 530
             .|...:|.|||::.|||..|:.||:.|:||...||.:::..|.|.|.|:|:||||:|.|.|:.:
Zfish   153 DNVSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 217

  Fly   531 -----GTK-NPLALQLM----AQGLYNHSTIPLTREEEELQELQEAASAAAA---KEPC 576
                 |.: .|....|:    |...|:.            |.|:.:.|.:||   .|.|
Zfish   218 THHRDGQEGEPSGFDLLEGTDASSPYSS------------QSLEVSGSGSAAPSESETC 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	529..554	CDD:431338	5/34 (15%)
hoxb2a	NP_571191.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..73		6/32 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..100		6/24 (25%)
		Antp-type hexapeptide	103..108		2/10 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	108..155		10/46 (22%)
		Homeodomain	159..215	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..338		14/66 (21%)
		PRK11907	237..>320	CDD:237019	9/40 (23%)