Protein Alignment inv and Tlx3

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 322
• Identity: 74/322 - (22%)
• Similarity: 109/322 - (33%)
• Gaps: 91/322 - (28%)

  Fly   325 NRSPLKAPKKSGKPLNLAQSNAAANSS-------LSFSSSLANICSNSNDSNSTATSSSTTNTSG 382
            |..|..:|....:|....:..|.|::.       :||.   .:...||.|.:|..........|
Mouse    29 NGDPAASPPSPAQPFRPPRMEAPASAQTPHPHEPISFG---IDQILNSPDQDSAPAPRGPDGAS- 89

  Fly   383 APVDLVKSPP-----------PAAGAGATGASGKSGEDSGTPIV----WPAWVYCTRYSDRPSSG 432
                .:..||           ||:.||.    |...||:|:..|    .||.|.... :.||..|
Mouse    90 ----YLGGPPGGRPGAAYPSLPASFAGL----GAPFEDAGSYSVNLSLAPAGVIRVP-AHRPLPG 145

  Fly   433 RSPRARKPKKPATSSSAAGGGGGGV-----------------------------EKGEAADGGGV 468
            ..|.......||..|.......||:                             ..|........
Mouse   146 AVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTP 210

  Fly   469 PEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTK 533
            |:.|:|||:||..|:..|:..|:..:||....|..|:..|.:.:||:|.||||:|.|.::.:..:
Mouse   211 PKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEE 275

  Fly   534 --------NPLALQLMAQG---------------LYNHSTIPLTREEEELQELQEAASAAAA 572
                    :.|.|||....               |:|.|...|    :.||..:|.:|...|
Mouse   276 REAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFAL----QNLQPWEEDSSKVPA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	7/47 (15%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	16/87 (18%)
		Homeodomain	214..270	CDD:459649	23/55 (42%)