Protein Alignment inv and Gbx1

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_056554.1
• Gene: Gbx1 / 231044
• MGIID: 95667
• Length: 418
• Species: Mus musculus
• Alignment Length: 330
• Identity: 88/330 - (26%)
• Similarity: 124/330 - (37%)
• Gaps: 90/330 - (27%)

  Fly   297 GALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPL-KAPKKSG-------------KPLNLAQSNAA 347
            |:......||...|.|.|||...|......|.: ..|.:||             :||.|.|:.|.
Mouse    58 GSAMQRAAGGGAPGGSGGSSGGPGAAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAP 122

  Fly   348 A---------NSSLSFSSSLAN-ICSNSNDSNSTATSSSTTNTSGA-PVDLVKSPPPAAGAGATG 401
            |         ....||:..|:| .|:....:..:..:.:|...|.| |.|....||..|.|.|:.
Mouse   123 APLPAGLPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAAAST 187

  Fly   402 ASGKSGEDSG--------------------TPIVWPAWVYCTRYSDRPSSGR--SPRARKPKKPA 444
            ||..:.|.:.                    .|...|...:...:...|:.|:  |....|.:.||
Mouse   188 ASRSNPEPAARRTDGALDAEELLPAREKVTEPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEPPA 252

  Fly   445 ---------------------TSSSAAGGG-------------GGGVEKG-EAADGGGVP--EDK 472
                                 ..|||.|.|             |.|.|:| ..|.|...|  :.:
Mouse   253 GDPAGSEQEEEGSGGDSEDSFLDSSAGGPGALLGPKPKLKGSPGTGAEEGTPVATGVTTPGGKSR 317

  Fly   473 RPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK------SSG 531
            |.||||:..||..|:.||:..:||:...|.|::..|.|:|.|:||||||:|||.|:      ||.
Mouse   318 RRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSR 382

  Fly   532 TKNPL 536
            :..|:
Mouse   383 SGEPV 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	27/55 (49%)
		Engrail_1_C_sig	529..554	CDD:431338	3/8 (38%)
Gbx1	NP_056554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		10/31 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..320		21/105 (20%)
		Homeodomain	317..373	CDD:459649	27/55 (49%)