Protein Alignment inv and EMX1

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 72/294 - (24%)
• Similarity: 95/294 - (32%)
• Gaps: 131/294 - (44%)

  Fly   279 FSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLKAPKKSGKPLNLAQ 343
            |:|::::..|        |...|..|||                 |..|.|.|...|.:||.
Human    43 FTIESLVAKD--------GGTGGGTGGG-----------------GAGSHLLAAAASEEPLR--- 79

  Fly   344 SNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAAGAGA--------- 399
                                        .|:.:..:.|.|....|...|.||.|||
Human    80 ----------------------------PTALNYPHPSAAEAAFVSGFPAAAAAGAGRSLYGGPE 116

  Fly   400 -------------------TGASGKS------GEDSGTPIVWPAWVYCTRY-------SDRPSSG 432
                               .|||...      |.....|:.:..||...|:       ||.|..|
Human   117 LVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDG 181

  Fly   433 ---RSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENR 494
               ..|.||||                               ||.|||||.:||.||:..|.:|.
Human   182 LLLHGPFARKP-------------------------------KRIRTAFSPSQLLRLERAFEKNH 215

  Fly   495 YLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKK 528
            |:....|:||:|.|.|:|.|:|:||||:|.|.|:
Human   216 YVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKR 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	29/55 (53%)
		Engrail_1_C_sig	529..554	CDD:431338	72/294 (24%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		0/1 (0%)