Protein Alignment inv and NKX2-3

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 129
• Identity: 42/129 - (32%)
• Similarity: 60/129 - (46%)
• Gaps: 20/129 - (15%)

  Fly   428 RPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGGGVPEDKR-PRTAFSGTQLARLKHEFN 491
            |..|.:|.:.:|..:.|....||       |:.|...    |..:| ||..||..|:..|:..|.
Human   115 RDRSQKSCQLKKSLETAGDCKAA-------EESERPK----PRSRRKPRVLFSQAQVFELERRFK 168

  Fly   492 ENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTR 555
            :.|||:...|:.|:..|.|...|:||||||:|.|.|:....|   :|:|.|     |:..|..|
Human   169 QQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDK---SLELGA-----HAPPPPPR 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	24/56 (43%)
		Engrail_1_C_sig	529..554	CDD:431338	6/24 (25%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		7/31 (23%)
		Homeodomain	149..205	CDD:459649	24/55 (44%)