Protein Alignment inv and NKX2-6

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 46/152 - (30%)
• Similarity: 64/152 - (42%)
• Gaps: 35/152 - (23%)

  Fly   427 DRPSSGRSP--------------RARKPKKPATSSSAAGGGGGGVEKGEAADG----GGVPED-- 471
            ||...|..|              |..:|:....::|..|||....|:|....|    ||..|.
Human    64 DRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPK 128

  Fly   472 ----KRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGT 532
                ::||..||..|:..|:..|.:.|||:...|:.|:..|.|...|:||||||:|.|.|:....
Human   129 ARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQD 193

  Fly   533 KNPLALQLMAQGLYNHSTIPLT 554
            |   :|:|...        |||
Human   194 K---SLELAGH--------PLT 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	4/24 (17%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		16/70 (23%)
		Homeodomain	133..189	CDD:459649	23/55 (42%)