Protein Alignment inv and Dlx3

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_034185.1
• Gene: Dlx3 / 13393
• MGIID: 94903
• Length: 287
• Species: Mus musculus
• Alignment Length: 218
• Identity: 59/218 - (27%)
• Similarity: 88/218 - (40%)
• Gaps: 58/218 - (26%)

  Fly   355 SSSLANICSNSNDSNSTATSSSTTNT-----------SGAPVDLVKSPPP------AAGAGATGA 402
            ||||:  |...:..:.|...|:.|:.           ||.|.....:|..      ..|...|||
Mouse    17 SSSLS--CHAGSKDSPTLPESTVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGA 79

  Fly   403 -SGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEKGEAADGG 466
             |.||....|     .::.....|.::|...:.|.:.|.:..|                |.....
Mouse    80 YSPKSEYTYG-----GSYRQYGAYREQPLPAQDPVSVKEEPEA----------------EVRMVN 123

  Fly   467 GVPED-KRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSS 530
            |.|:. ::|||.:|..|||.|:..|.:.:||....|.:|:.:|||.:.|:||||||:|:|.||
Mouse   124 GKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK-- 186

  Fly   531 GTKNPLALQLMAQGLYNHSTIPL 553
                          ||.:..:||
Mouse   187 --------------LYKNGEVPL 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	529..554	CDD:431338	4/25 (16%)
Dlx3	NP_034185.1	DLL_N	27..107	CDD:463567	17/84 (20%)
		COG5576	<109..224	CDD:227863	36/119 (30%)
		Homeodomain	130..186	CDD:459649	25/55 (45%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:O60479	131..181		23/49 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		1/1 (100%)