Protein Alignment inv and Dlx2

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 275
• Identity: 69/275 - (25%)
• Similarity: 92/275 - (33%)
• Gaps: 117/275 - (42%)

  Fly   367 DSNST-ATSSSTTNTSGAPVDLVKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPS 430
            |.:|| .|:|||.:..       :.||..||||..|.|..|..:|..              .:|.
Mouse    11 DMHSTQITASSTYHQH-------QQPPSGAGAGPGGNSNSSSSNSSL--------------HKPQ 54

  Fly   431 SGRSPRARKPKKPATSSS-------AAGGGGGGVE------------------------------ 458
              .||..  |...||.||       .|||||||..
Mouse    55 --ESPTL--PVSTATDSSYYTNQQHPAGGGGGGASPYAHMGSYQYHASGLNNVSYSAKSSYDLGY 115

  Fly   459 --------------------------KGEAADGGGVPED-KRPRTAFSGTQLARLKHEFNENRYL 496
                                      :.|.....|.|:. ::|||.:|..|||.|:..|.:.:||
Mouse   116 TAAYTSYAPYGTSSSPVNNEPDKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYL 180

  Fly   497 TEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEELQ 561
            ....|.:|:..|||.:.|:||||||:|:|.||                ::....||
Mouse   181 ALPERAELAASLGLTQTQVKIWFQNRRSKFKK----------------MWKSGEIP--------- 220

  Fly   562 ELQEAASAAAAKEPC 576
              .|....|:|..||
Mouse   221 --TEQHPGASASPPC 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	529..554	CDD:431338	2/24 (8%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		26/88 (30%)
		DLL_N	54..135	CDD:463567	14/84 (17%)
		Homeodomain	156..212	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		7/26 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332