Protein Alignment inv and en2

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_002932525.1
• Gene: en2 / 100498251
• XenbaseID: XB-GENE-853108
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 291
• Identity: 124/291 - (42%)
• Similarity: 152/291 - (52%)
• Gaps: 75/291 - (25%)

  Fly   269 NENLHERALKFSIDNILKADFGSRLPKI--------GALSGNIGGGSVSGSSTGSSKNSGNTNGN 325
            |...|.|...|.|||||:.:||.|...|        |..||.:.|...:.....:::.:|   |:
 Frog    32 NHQPHHRITNFFIDNILRPEFGRRKEGISHQDELFSGRDSGALSGAESAHHRANATEGAG---GS 93

  Fly   326 RS-PLKAPKKSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVK 389
            :: .|...|||...:..:..:...|...|.||          ||:|:..||.|
 Frog    94 KAITLTGDKKSDIAMEESLKSRGHNGDHSLSS----------DSDSSQASSKT------------ 136

  Fly   390 SPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGG 454
                                |..|::|||||||||||||||||  ||:|||||..|::
 Frog   137 --------------------SQQPMLWPAWVYCTRYSDRPSSG--PRSRKPKKKTTTT------- 172

  Fly   455 GGVEKGEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWF 519
              |.|          |||||||||:..||.|||.||..||||||:|||.|:.||.|||:||||||
 Frog   173 --VTK----------EDKRPRTAFTADQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWF 225

  Fly   520 QNKRAKLKKSSGTKNPLALQLMAQGLYNHST 550
            ||||||:||::|.||.|||.|||||||||||
 Frog   226 QNKRAKIKKATGNKNSLALHLMAQGLYNHST 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	41/55 (75%)
		Engrail_1_C_sig	529..554	CDD:431338	17/22 (77%)
en2	XP_002932525.1	Homeodomain	178..234	CDD:459649	41/55 (75%)
		Engrail_1_C_sig	235..265	CDD:431338	17/22 (77%)