Protein Alignment inv and nkx2-3

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_002937234.1
• Gene: nkx2-3 / 100486189
• XenbaseID: XB-GENE-852996
• Length: 328
• Species: Xenopus tropicalis
• Alignment Length: 232
• Identity: 60/232 - (25%)
• Similarity: 88/232 - (37%)
• Gaps: 42/232 - (18%)

  Fly   327 SPLKAPKKSGKP-LNLAQSNAAANSSLSFSSSLANICSNSN------DSNSTATSSSTTNTSGAP 384
            ||:.:...|.|. |||.|.   ....::....|...||.::      |.:|....:|....:|..
 Frog     5 SPVTSTPFSVKDILNLEQQ---GQPPIAHPQHLQQQCSRAHPAHPAQDLDSDFQQASCMLAAGER 66

  Fly   385 VDLVKSPPPAAGAGATGASGKSGEDSGTPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSA 449
            ..............|.||:...|:...:|             ||..:.|.|   |.:......|.
 Frog    67 CVYAGGEDKLPFLSAMGAAEPHGDVGLSP-------------DRYVALRDP---KEEDEEEEDSL 115

  Fly   450 AGGGGGGVEKGEAADGGGVPED---------KRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLS 505
            ..||.......::.||.|..||         ::||..||..|:..|:..|.:.|||:...|:.|:
 Frog   116 REGGNKSCFLNKSPDGEGKLEDPDRPKQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLA 180

  Fly   506 GELGLNEAQIKIWFQNKRAKLKK-------SSGTKNP 535
            ..|.|...|:||||||:|.|.|:       ..||.:|
 Frog   181 NSLKLTSTQVKIWFQNRRYKCKRQRQDKSLEMGTHHP 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	3/7 (43%)
nkx2-3	XP_002937234.1	Homeodomain	147..203	CDD:459649	23/55 (42%)