Protein Alignment inv and nkx6-2

DIOPT Version :10

• Sequence 1: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_002937836.1
• Gene: nkx6-2 / 100038084
• XenbaseID: XB-GENE-484527
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 301
• Identity: 75/301 - (24%)
• Similarity: 109/301 - (36%)
• Gaps: 90/301 - (29%)

  Fly   266 LNNNENLHERALKFSIDNILKADFGSRLPKIGALSGNIGGGSVSGSSTGSSKNSGNTNGNRSPLK 330
            |:|...:......:::.|   ..|  :.|.:.:||..|..|:..|.|...|:..|.|.|
 Frog    25 LHNMAEMKTTLFPYALQN---PSF--KAPGLSSLSAQIPLGTPHGISDILSRPLGATLG------ 78

  Fly   331 APKKSGKPLNLAQSNAAANSSLSFSSSLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPPPAA 395
                               ||.:..|||..|       |..|||   |.....|..:.:.|.|.|
 Frog    79 -------------------SSANLLSSLPRI-------NGLATS---TGMYFNPAAVSRYPKPLA 114

  Fly   396 GAGATGASGKSGEDSG-TPIVWPAWVYCTRYSDRPSSGRSPRARKPKKPATSSSAAGGGGGGVEK 459
                        |..| .||.||..:       :.|..|.||...|.                :.
 Frog   115 ------------ELPGRAPIFWPGVM-------QGSPWRDPRLGCPS----------------QA 144

  Fly   460 GEAADGGGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRA 524
            |...|..|..:..||  .|||.|:..|:..|.:.:||....|.:|:..||:.|:|:|:||||:|.
 Frog   145 GMVLDKDGKKKHSRP--TFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRT 207

  Fly   525 KLKKSSGTKNPLALQLMAQGLYNHSTIPLTREEEELQELQE 565
            |.:|....:       ||.....|.:     |.|:::|..|
 Frog   208 KWRKRHAAE-------MATAKKKHDS-----ETEKMKESSE 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	529..554	CDD:431338	3/24 (13%)
nkx6-2	XP_002937836.1	Homeodomain	153..211	CDD:459649	23/59 (39%)