Protein Alignment iotaTry and PRSS53

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 59/279 - (21%)
• Similarity: 103/279 - (36%)
• Gaps: 85/279 - (30%)

  Fly    40 PWQVSIQISARHECGGVIYSKEIIITAGHCLHERSVTLM---KVRVGA---QNHNYGGTLVPVAA 98
            |||.|::....|.|.|.:.:...::||.||..:.:.|.:   .|.:|:   :..:.|...|.|||
Human    49 PWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAA 113

  Fly    99 YKVHEQFDSRFLHY----DIAVLRLSTPLTFGLSTRAINLASTSPSG----GTTVTVTGWGH-TD 154
            .::...::    ||    |:|:|:|:.|.|.      ..|....|:.    |.:...|||.. |.
Human   114 LQLPRAYN----HYSQGSDLALLQLAHPTTH------TPLCLPQPAHRFPFGASCWATGWDQDTS 168

  Fly   155 NG------------------------------------------ALS---DSLQKAQLQIIDRGE 174
            :|                                          :||   .:|:..:|::|.|..
Human   169 DGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPT 233

  Fly   175 C------ASQKFGYGADFVGEETICAASTDA--DACTGDSGGPLVASSQ-----LVGIVSWGYRC 226
            |      ..|:  :.::......:|......  ..|.||||||::....     ..||:|:...|
Human   234 CNCIYNQLHQR--HLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSC 296

  Fly   227 ADDNYPGVYADVAILRPWI 245
            |.::.|.:..:.|....|:
Human   297 AQEDAPVLLTNTAAHSSWL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	58/277 (21%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	59/279 (21%)
		Tryp_SPc	359..>512	CDD:473915