Protein Alignment iotaTry and Prss22

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 280
• Identity: 85/280 - (30%)
• Similarity: 128/280 - (45%)
• Gaps: 40/280 - (14%)

  Fly     9 TVLVLLLLGDASDVEAT--------------GRIIGGSDQLIRNAPWQVSIQISARHECGGVIYS 59
            |:::|:||...:.|.|.              .|::||.|......||.|||..:..|.|.|.:.:
  Rat    17 TLILLVLLTSTATVSAANIRGSPDCGKPQQLNRVVGGEDSADAQWPWIVSILKNGSHHCAGSLLT 81

  Fly    60 KEIIITAGHCLHER-------SVTLMKVRVGAQNHNYGGTLVPVAAYKVHEQFDSR-FLHYDIAV 116
            ...:::|.||....       ||.|...::|  |.......|.:|:...|.::..: ..|.|||:
  Rat    82 NRWVVSAAHCFSSNMDKPSPYSVLLGAWKLG--NPGPRSQKVGIASVLPHPRYSRKEGTHADIAL 144

  Fly   117 LRLSTPLTFGLSTRAINLASTS----PSGGTTVTVTGWGHTDNGA---LSDSLQKAQLQIIDRGE 174
            :||..|:.|......|.|..:|    |:  |...:.|||...:|.   ...:|||.::.|||...
  Rat   145 VRLERPIQFSERILPICLPDSSVHLPPN--TNCWIAGWGSIQDGVPLPRPQTLQKLKVPIIDPEL 207

  Fly   175 CASQKF-GYGADFVGEETICAASTDA--DACTGDSGGPLVASSQ----LVGIVSWGYRCADDNYP 232
            |.|..: |.|.:.:.|:.:||...:.  |||.|||||||:....    |.||:|||..||:.|.|
  Rat   208 CKSLYWRGAGQEAITEDMLCAGYLEGKRDACLGDSGGPLMCQVDDHWLLTGIISWGEGCAERNRP 272

  Fly   233 GVYADVAILRPWIVKAANAI 252
            |||..:...|||:.:....:
  Rat   273 GVYTSLLAHRPWVQRIVQGV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	78/239 (33%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	78/241 (32%)