Protein Alignment iotaTry and KLK9

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_036447.1
• Gene: KLK9 / 284366
• HGNCID: 6370
• Length: 250
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 74/259 - (28%)
• Similarity: 112/259 - (43%)
• Gaps: 36/259 - (13%)

  Fly     5 GIVATVLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHC 69
            |::..:|.||    |....|..|.||..:....:.|||..:....|..||..:.|...::||.||
Human     4 GLLCALLSLL----AGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHC 64

  Fly    70 LHERSVTLMKVRVGAQNH--NYGG--TLVPVAAYKVHEQFDSRFL----HYDIAVLRLSTPLTFG 126
               |...|. ||:| ::|  .:.|  .|..|..:..|..|:....    :.||.::||.......
Human    65 ---RKPYLW-VRLG-EHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLS 124

  Fly   127 LSTRAINLASTSPSGGTTVTVTGWGHTDNGALSD-------SLQKAQLQIIDRGECASQKFGYGA 184
            .:.:.:||:.|..|.|....::||     ||:|.       :||.|.:.|::...|.....|:
Human   125 PAVQPLNLSQTCVSPGMQCLISGW-----GAVSSPKALFPVTLQCANISILENKLCHWAYPGH-- 182

  Fly   185 DFVGEETICAASTDA--DACTGDSGGPLVASSQLVGIVSWGYR-CADDNYPGVYADVAILRPWI 245
              :.:..:||...:.  .:|.||||||||.:..|.|:||.|.. |:....|.||..|.....||
Human   183 --ISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWI 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	66/235 (28%)
KLK9	NP_036447.1	Tryp_SPc	24..247	CDD:238113	67/235 (29%)