DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and tmprss5

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	256	Identity:	95/256 - (37%)
Similarity:	133/256 - (51%)	Gaps:	42/256 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVASQYKVVAG 102
            ||:||....:.:.|:|:||.|..        ||.|||||.....||||||||     ..|::...
Zfish   311 RIIGGVEAALGRWPWQVSLYYNN--------RHICGGSIITNQWIVTAAHCV-----HNYRLPQV 362

  Fly   103 TNFQTGSDGVITNVKEIVMHEGY----------YSGAAYNNDIAILFVDPPLPLNNF--TIKAIK 155
            .::...:..:.:|:.::..::|:          |:...::||||::.:..||   ||  ||:.:.
Zfish   363 PSWVVYAGIITSNLAKLAQYQGFAVERIIYNKNYNHRTHDNDIALVKLKTPL---NFSDTIRPVC 424

  Fly   156 LAL---EQPIEGTVSKVSGWGTTSPGGYSSNQLL-AVDVPIVSNELCDQDYEDFGDETYRITSAM 216
            |..   :.| .||...:||||.|.|......::| ...||::|.:.|:......|:    |||.|
Zfish   425 LPQYDHDLP-GGTQCWISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCMYNGE----ITSRM 484

  Fly   217 LCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGVYANVAYLRPWI 273
            |||| ...|..|||||||||||..:||    |.||||||..||.||:||||:.||....||
Zfish   485 LCAG-YSEGKVDACQGDSGGPLVCQDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWI 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	93/254 (37%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	94/255 (37%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	93/254 (37%)
		Tryp_SPc	312..547	CDD:238113	94/255 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910