Protein Alignment zetaTry and PRSS2

DIOPT Version :10

• Sequence 1: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 98/283 - (34%)
• Similarity: 137/283 - (48%)
• Gaps: 41/283 - (14%)

  Fly    10 LAFLVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGG 74
            |..:::.||.....|    .|:    |.:|||||..:...||||:||         |...|.|||
Human     3 LLLILTFVAAAVAAP----FDD----DDKIVGGYICEENSVPYQVSL---------NSGYHFCGG 50

  Fly    75 SIFNETTIVTAAHCVIGTVAS----------QYKVVAGT-NFQT--GSDGVITNVKEIVMHEGYY 126
            |:.:|..:|:|.||....:.|          :.:|..|. |.:.  |::..| |..:|:.|..|.
Human    51 SLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFI-NAAKIIRHPKYN 114

  Fly   127 SGAAYNNDIAILFVDPPLPLNNFTIKAIKLALEQPIEGTVSKVSGWGTT-SPGGYSSNQLLAVDV 190
            | ...:|||.::.:..|..:|: .:.||.|....|..||.|.:||||.| |.|....::|..:|.
Human   115 S-RTLDNDILLIKLSSPAVINS-RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDA 177

  Fly   191 PIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDELYGVVSWGNSCA 255
            |::|...|:..|..      :||:.|.|.|.. .||.|:||||||||:....||.|:||||..||
Human   178 PVLSQAECEASYPG------KITNNMFCVGFL-EGGKDSCQGDSGGPVVSNGELQGIVSWGYGCA 235

  Fly   256 LPNYPGVYANVAYLRPWIDAVLA 278
            ..|.||||..|.....||...:|
Human   236 QKNRPGVYTKVYNYVDWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	89/248 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	91/250 (36%)