DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and Tmprss4

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	90/287 - (31%)
Similarity:	124/287 - (43%)	Gaps:	71/287 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LVSLVALTQGLPLLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIF 77
            ||||..|..|         ||:...|:|||........|:|:|::|..        :|.|||||.
  Rat   229 LVSLRCLDCG---------KSLKTTRVVGGVEASADSWPWQVSIQYNK--------QHVCGGSIL 276

  Fly    78 NETTIVTAAHCVIGTV-ASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVD 141
            :...|:|||||....: .|.:||.||:|....|..:                     .:|.:|:.
  Rat   277 DHHWILTAAHCFRKYLDVSSWKVRAGSNKLGNSPSL---------------------PVAKIFIA 320

  Fly   142 PPLPL--NNFTIKAIKLALEQPIEGTVSK-----------------VSGWG-TTSPGGYSSNQLL 186
            .|.||  ....|..:||.:.....|:|..                 |.||| |...||..|:.||
  Rat   321 EPNPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVIGWGFTEENGGKMSDTLL 385

  Fly   187 AVDVPIVSNELCDQDYEDFGDETYR--ITSAMLCAGKRGVGGADACQGDSGGPLAV---RDELYG 246
            ...|.::.:..|:      .::.|:  :|:.||||| ...||.|.|||||||||..   :.::.|
  Rat   386 QASVQVIDSARCN------AEDAYQGEVTAGMLCAG-TPQGGKDTCQGDSGGPLMYHYDKWQVVG 443

  Fly   247 VVSWGNSCALPNYPGVYANVAYLRPWI 273
            :||||..|..|:.||||..|.....||
  Rat   444 IVSWGYGCGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	80/260 (31%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	81/261 (31%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	5/8 (63%)
		Tryp_SPc	245..470	CDD:214473	80/260 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910