Protein Alignment lambdaTry and KLK4

DIOPT Version :10

• Sequence 1: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 76/255 - (29%)
• Similarity: 117/255 - (45%)
• Gaps: 19/255 - (7%)

  Fly     8 FLVLGVGCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQII 72
            :|:|||..||           :.....:|:.|:|.:....|.|.::.......|.|.:.....::
Human    14 YLILGVAGSL-----------VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVL 67

  Fly    73 SAAHCVNTLSGPENLTIVAGSSNIWFPTGP-QQELEVREIIIHPKYRTLNNDYDAAILILDGDFE 136
            |||||..     .:.||..|..::.....| .|.:|....:.||:|.......|..::.||....
Human    68 SAAHCFQ-----NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVS 127

  Fly   137 FNDAVQPIELAKERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRML 201
            .:|.::.|.:|.:.|.......|:|||..: .|.:..|||.|:|:||....|...|..:....|.
Human   128 ESDTIRSISIASQCPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMF 191

  Fly   202 CAGVNGGGKDACQGDSGGPLVYNNTLLGIVSWGTG-CAREKYPGVYCSVPDVLDWLVETV 260
            |||.....||:|.|||||||:.|..|.|:||:|.. |.:...||||.::....:|:.:||
Human   192 CAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	68/224 (30%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	68/224 (30%)