DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss5

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	241	Identity:	90/241 - (37%)
Similarity:	136/241 - (56%)	Gaps:	18/241 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPE--NLTIVAG--SSN 95
            ||:||.:..:.::|.|:|:.|...|.|||:|..:..|::|||||:....|:  :..:.||  :||
Zfish   311 RIIGGVEAALGRWPWQVSLYYNNRHICGGSIITNQWIVTAAHCVHNYRLPQVPSWVVYAGIITSN 375

  Fly    96 IWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTP---- 156
            : ......|...|..||.:..|....:|.|.|::.|.....|:|.::|:.|.:.  |||.|
Zfish   376 L-AKLAQYQGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNFSDTIRPVCLPQY--DHDLPGGTQ 437

  Fly   157 VTVTGWG-TTSEGGTISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDACQGDSG 218
            ..::||| |..:...|.:||:|..|.::....|.::  |:..:||||||||.:.|..||||||||
Zfish   438 CWISGWGYTQPDDVLIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVDACQGDSG 502

  Fly   219 GPLVYNN----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETV 260
            ||||..:    .|:|:||||||||...:||||..|.:.|.|:.:.:
Zfish   503 GPLVCQDENVWRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWIYDII 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	89/234 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	89/237 (38%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	89/235 (38%)
		Tryp_SPc	312..547	CDD:238113	89/237 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910