Protein Alignment lambdaTry and KLK15

DIOPT Version :10

• Sequence 1: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 77/241 - (31%)
• Similarity: 119/241 - (49%)
• Gaps: 18/241 - (7%)

  Fly    33 DG-RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNI 96
            || :::.|.:......|.|:::..||...||.::...:.::|||||.:..     :.:..|..|:
Human    18 DGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRF-----MRVRLGEHNL 77

  Fly    97 WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPVTVTG 161
            ....||:|......:|.||:|...::..|..:|.|......|..|:|..|....|.......|:|
Human    78 RKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSG 142

  Fly   162 WGTTS--EGGT---------ISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQG 215
            ||..|  |.||         :.|.|...:::::.:::|..:|...||:.|:|||..|.|.::|:|
Human   143 WGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEG 207

  Fly   216 DSGGPLVYNNTLLGIVSWG-TGCAREKYPGVYCSVPDVLDWLVETV 260
            |||||||....|.|||||| ..|.....||||..|...|:|:.||:
Human   208 DSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETM 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	73/234 (31%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	72/228 (32%)