Protein Alignment lambdaTry and F12

DIOPT Version :10

• Sequence 1: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 86/241 - (35%)
• Similarity: 117/241 - (48%)
• Gaps: 18/241 - (7%)

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFP 99
            |:|||.......:|: |:..|.|:..|.|::.....:::||||:.....||:||:|.|.......
Human   372 RVVGGLVALRGAHPY-IAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHS 435

  Fly   100 TGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDA-----VQPIEL--AKERPDHDTPV 157
            ..|.|.|.||...:|..:..::..:|.|:|.|..|.:.:.|     |||:.|  ...||...|..
Human   436 CEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLC 500

  Fly   158 TVTGWGTTSEGG-TISDVLQEVSVNVVDNSNCK--NAYSIMLTSRMLCAGVNGGGKDACQGDSGG 219
            .|.|||...||. ..:..|||..|..:....|.  :.:...:...|||||...||.|||||||||
Human   501 QVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGG 565

  Fly   220 PLVYNN-------TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVE 258
            |||..:       ||.||:|||:||.....||||..|...|.|:.|
Human   566 PLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIRE 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	85/240 (35%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359
		Tryp_SPc	373..612	CDD:238113	85/240 (35%)