Protein Alignment lambdaTry and F7

DIOPT Version :10

• Sequence 1: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 89/278 - (32%)
• Similarity: 130/278 - (46%)
• Gaps: 25/278 - (8%)

  Fly    12 GVGCSLA-------DPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSN 69
            ||.|:..       .||.  |:.:..|..||||||:.....:.|.|:.:...|...||||:..:.
Human   213 GVSCTPTVEYPCGKIPIL--EKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTI 275

  Fly    70 QIISAAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGD 134
            .::|||||.:.:....||..|.|..::....|.:|...|.::||...|.....::|.|:|.|...
Human   276 WVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQP 340

  Fly   135 FEFNDAVQPIELAKERPDHDTPVT------VTGWGTTSEGGTISDVLQEVSVNVVDNSNC----- 188
            ....|.|.|:.| .||...:..:.      |:|||...:.|..:..|..::|..:...:|
Human   341 VVLTDHVVPLCL-PERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSR 404

  Fly   189 KNAYSIMLTSRMLCAGVNGGGKDACQGDSGGPLV--YNNT--LLGIVSWGTGCAREKYPGVYCSV 249
            |...|..:|..|.|||.:.|.||:|:||||||..  |..|  |.||||||.|||...:.|||..|
Human   405 KVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRV 469

  Fly   250 PDVLDWLVETVADKESVG 267
            ...::||.:.:..:...|
Human   470 SQYIEWLQKLMRSEPRPG 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	79/237 (33%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	2/2 (100%)
		Tryp_SPc	242..478	CDD:238113	79/236 (33%)