Protein Alignment lambdaTry and KLK8

DIOPT Version :10

• Sequence 1: NP_610673.1
• Gene: lambdaTry / 36214
• FlyBaseID: FBgn0043470
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 86/275 - (31%)
• Similarity: 131/275 - (47%)
• Gaps: 37/275 - (13%)

  Fly    15 CSLADPIYRNEEVHIPK----------------LDGRIVGGQDTNITQYPHQISMRYRGNH-RCG 62
            |...:|.:.::..|.|:                .:.:::||.:......|.|.:: ::|.. .||
Human    41 CVHLNPQWPSQPSHCPRGWRSNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAAL-FQGQQLLCG 104

  Fly    63 GTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTL---NNDY 124
            |.:...|.:::||||..     ...|:..|..::....||:||:.|.:.|.||.|.:.   ::::
Human   105 GVLVGGNWVLTAAHCKK-----PKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNH 164

  Fly   125 DAAILILDGDFEFNDAVQPIELAKERPDHDT----PVTVTGWGT-TSEGGTISDVLQEVSVNVVD 184
            |..:|.|.........|:||.||    ||.|    ..||:|||| ||......|.|....|.:..
Human   165 DLMLLQLRDQASLGSKVKPISLA----DHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 225

  Fly   185 NSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDSGGPLVYNNTLLGIVSWGTG-CAREKYPGVYCS 248
            ...|::||...:|..|:||| :..|.|.||||||||||.:..|.||.|||:. |.|...||||.:
Human   226 QKKCEDAYPGQITDGMVCAG-SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTN 289

  Fly   249 VPDVLDWLVETVADK 263
            :...|||:.:.:..|
Human   290 ICRYLDWIKKIIGSK 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	81/232 (35%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	80/230 (35%)