DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and Tigd3

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_001101043.1	Gene:	Tigd3 / 309174	RGDID:	1305393	Length:	470	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	54/193 - (27%)
Similarity:	95/193 - (49%)	Gaps:	27/193 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKPRTSLTLEEKMEVIQSQERNKLSVRDLAKRFNIGKTQAADILKHKQSIKEGLLSGELKLNQMR 71
            :|...:|:|.||::|::..:.:|:|..::|:||.:.:.|.:.|.|:|:.:.....||  ..|..|
  Rat     6 KKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSG--TANHER 68

  Fly    72 RNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVELGHSNFSASSGWLEKWRKRHN 136
            :.....:.:.|||....|:...|.:...::|.|:..|||:||..:| .:|..|.|||.:|::|:|
  Rat    69 KRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMG-QDFVPSIGWLVRWKRRNN 132

  Fly   137 VRYNDTGDSLDLQEFEAILVKSEPISNKDDCDEPYPVTLIEPIYSTEEAMMQLARLKEFAKDD 199
            |.:..          ..:||...|         |.|    .|..|..:|...|: ||:|:.:|
  Rat   133 VGFGT----------RQVLVPLLP---------PEP----PPAVSPSQAQPPLS-LKDFSPED 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	15/52 (29%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	22/62 (35%)
Tigd3	NP_001101043.1	HTH	6..57	CDD:419669	15/50 (30%)
		HTH_Tnp_Tc5	76..133	CDD:397365	20/57 (35%)
		rve	193..360	CDD:419726
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1343623at2759
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	1	1.000	-	-		otm44569
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820