DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and TIGD3

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_663771.1	Gene:	TIGD3 / 220359	HGNCID:	18334	Length:	471	Species:	Homo sapiens

Alignment Length:	193	Identity:	55/193 - (28%)
Similarity:	98/193 - (50%)	Gaps:	27/193 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKPRTSLTLEEKMEVIQSQERNKLSVRDLAKRFNIGKTQAADILKHKQSIKEGLLSGELKLNQMR 71
            :|...:|:|.||::|::..:.:|:|..::|:||.:.:.|.:.|.|:|:.:.....||  ..|:.|
Human     6 KKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSG--TANRER 68

  Fly    72 RNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVELGHSNFSASSGWLEKWRKRHN 136
            :.....:.:.|||....|:...|.:...::|.|:..|||:||..:| .:|..|.|||.:|::|:|
Human    69 KRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMG-QDFVPSIGWLVRWKRRNN 132

  Fly   137 VRYNDTGDSLDLQEFEAILVKSEPISNKDDCDEPYPVTLIEPIYSTEEAMMQLARLKEFAKDD 199
            |.:.          ...:|..|.|       .||.|..|      |.:|.:.|: ||:|:.:|
Human   133 VGFG----------ARHVLAPSFP-------PEPPPPGL------TSQAQLPLS-LKDFSPED 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	15/52 (29%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	22/62 (35%)
TIGD3	NP_663771.1	HTH	6..57	CDD:328727	15/50 (30%)
		HTH_Tnp_Tc5	76..133	CDD:308705	20/57 (35%)
		rve	193..360	CDD:328789
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1343623at2759
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850