DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cag and Jrk

DIOPT Version :9

Sequence 1:	NP_001260876.1	Gene:	cag / 36157	FlyBaseID:	FBgn0017414	Length:	225	Species:	Drosophila melanogaster
Sequence 2:	NP_032441.4	Gene:	Jrk / 16469	MGIID:	106214	Length:	557	Species:	Mus musculus

Alignment Length:	208	Identity:	55/208 - (26%)
Similarity:	91/208 - (43%)	Gaps:	28/208 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GRVRKPRTSLTLEEKMEVIQSQERNKLSVRDLAKRFNIGKTQAADILKHKQSIKEGLLSGELK-- 66
            |..|| |..|||:||:::....||.: |.:.|.:.:|:|.:...||..||..:.....|.:.:
Mouse    12 GEKRK-RVVLTLKEKIDICTRLERGE-SRKALMQEYNVGMSTLYDIKAHKAQLLRFFASSDSRQA 74

  Fly    67 LNQMRRNPLSQRGAQIDEMCFDWFSRVRTENIPISGEMVRKKAKQLAVELGHSNFSA-SSGWLEK 130
            |.| ||...:.:...:|.:.::||...|.|.||:||.|:.:|||....::..:.... |.|||.:
Mouse    75 LEQ-RRTLHTPKLEHLDRVLYEWFLVKRAEGIPVSGPMLIEKAKDFYKQMRLTEPCVFSGGWLWR 138

  Fly   131 WRKRHNVRYNDTGDSLDLQEFEAI---------LVKSEPISNKDDCDEPYPVTLIEPIYSTEEAM 186
            ::.||.::..|........:.:|.         |.....:|.             |.:||.:|..
Mouse   139 FKARHGIKKLDASSEKQAADHQAAEQFCGFFRSLAAEHGLSP-------------EQVYSADETG 190

  Fly   187 MQLARLKEFAKDD 199
            :....|...|.||
Mouse   191 LVWRCLPNSAPDD 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cag	NP_001260876.1	CENP-B_N	7..60	CDD:282122	18/52 (35%)
cag	NP_001260876.1	CENPB	78..141	CDD:197828	19/63 (30%)
Jrk	NP_032441.4	CENP-B_N	14..66	CDD:282122	18/53 (34%)
		CENPB	83..147	CDD:197828	19/63 (30%)
		DDE_1	213..382	CDD:281213
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3105
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1343623at2759
OrthoFinder	1	1.000	-	-		FOG0000365
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820