Protein Alignment CG12896 and Prdx6

DIOPT Version :10

• Sequence 1: NP_610584.2
• Gene: CG12896 / 36101
• FlyBaseID: FBgn0033521
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_446028.1
• Gene: Prdx6 / 94167
• RGDID: 71005
• Length: 224
• Species: Rattus norvegicus
• Alignment Length: 216
• Identity: 115/216 - (53%)
• Similarity: 147/216 - (68%)
• Gaps: 2/216 - (0%)

  Fly     3 LGQTVPNFEADTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNTKCLAH 67
            ||...|||||:||.|.|:||::.|:||.:|||||.||||||||||||.|...|||||||.|.:|.
  Rat     7 LGDEAPNFEANTTIGHIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIAL 71

  Fly    68 SVDALNSHVDWVNDIKSYCLDIPGD-FPYPIIADPTRDLAVTLGMLDEEQKKDPEVGKTIRALFI 131
            |:|::..|..|..||.:|....|.: .|:|||.|..||||:.|||||..:|.:..:..|.|.:||
  Rat    72 SIDSVEDHFAWSKDINAYNGAAPTEKLPFPIIDDKDRDLAILLGMLDPAEKDEKGMPVTARVVFI 136

  Fly   132 ISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMILPSVTDDEAHK 196
            ..||.|::||:.||.:||||.|||||.:|||||| ....||||.:|..|..||:||::.::||.:
  Rat   137 FGPDKKLKLSILYPATTGRNFDEILRVVDSLQLT-ASNPVATPVDWKKGESVMVLPTLPEEEAKQ 200

  Fly   197 LFPKGFDKVSMPSGVNYVRTT 217
            |||||.....:|||..|:|.|
  Rat   201 LFPKGVFTKELPSGKKYLRYT 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12896	NP_610584.2	PRX_1cys	3..218	CDD:239314	115/216 (53%)
Prdx6	NP_446028.1	PRX_1cys	7..222	CDD:239314	115/216 (53%)
		Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000269|PubMed:19700648	31..40		5/8 (63%)